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Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019

OBJECTIVE: This study aimed to compare the postpartum outcomes of asymptomatic and symptomatic patients with coronavirus disease-2019 (COVID-19). METHODS: This retrospective cohort study included pregnant women with COVID-19. Pregnant women were categorized into two sets as asymptomatic and symptoma...

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Autores principales: VURAL, Tayfun, BAYRAKTAR, Burak, YILDIRIM KARACA, Suna, ODABAS, Ozan, YILMAZ, Nisel, SAMLIOGLU, Pınar, OZEREN, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939442/
https://www.ncbi.nlm.nih.gov/pubmed/35306785
http://dx.doi.org/10.4274/MMJ.galenos.2022.47600
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author VURAL, Tayfun
BAYRAKTAR, Burak
YILDIRIM KARACA, Suna
ODABAS, Ozan
YILMAZ, Nisel
SAMLIOGLU, Pınar
OZEREN, Mehmet
author_facet VURAL, Tayfun
BAYRAKTAR, Burak
YILDIRIM KARACA, Suna
ODABAS, Ozan
YILMAZ, Nisel
SAMLIOGLU, Pınar
OZEREN, Mehmet
author_sort VURAL, Tayfun
collection PubMed
description OBJECTIVE: This study aimed to compare the postpartum outcomes of asymptomatic and symptomatic patients with coronavirus disease-2019 (COVID-19). METHODS: This retrospective cohort study included pregnant women with COVID-19. Pregnant women were categorized into two sets as asymptomatic and symptomatic according to their clinics at the time of application. COVID-19 was diagnosed using the real-time reverse transcriptase-polymerase chain reaction on the oropharyngeal and nasopharyngeal swabs. Asymptomatic and symptomatic patients were compared in terms of maternal and perinatal outcomes. RESULTS: Our study population consisted of 20 asymptomatic and 41 symptomatic patients with laboratory-confirmed COVID-19. The rate of primary cesarean section was more than twice in the symptomatic group (51.2%) than that of the asymptomatic group (20%) (p=0.019). Both groups are quite similar in terms of maternal [respiratory support, COVID-19-related treatment, and intensive care unit (ICU) admission], perinatal (preterm delivery, preterm premature rupture of membrane, preeclampsia, and mode of delivery), and neonatal outcomes [birth weight, Apgar scores, neonatal ICU (NICU) admission]. The rate of total cesarean section in the asymptomatic group (75%) was statistically similar to the symptomatic group (83%) (p=0.464). The NICU admission rate was found to be similar in the asymptomatic (54.2%) and symptomatic groups (50%) (p=0.858). However, NICU admissions were more frequent in the symptomatic group due to respiratory distress (p=0.032). The breastfeeding rate is higher in the asymptomatic pregnant group as expected (p=0.015). Additionally, the ferritin level was significantly lower in the asymptomatic group (p=0.006). CONCLUSIONS: The rate of primary cesarean section is quite high in symptomatic patients with COVID-19. Additionally, the total cesarean section rate was extremely high in both groups. We expected more adverse outcomes in symptomatic patients; however, we found similar maternal, perinatal, and neonatal outcomes between both groups.
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spelling pubmed-89394422022-04-08 Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 VURAL, Tayfun BAYRAKTAR, Burak YILDIRIM KARACA, Suna ODABAS, Ozan YILMAZ, Nisel SAMLIOGLU, Pınar OZEREN, Mehmet Medeni Med J Original Article OBJECTIVE: This study aimed to compare the postpartum outcomes of asymptomatic and symptomatic patients with coronavirus disease-2019 (COVID-19). METHODS: This retrospective cohort study included pregnant women with COVID-19. Pregnant women were categorized into two sets as asymptomatic and symptomatic according to their clinics at the time of application. COVID-19 was diagnosed using the real-time reverse transcriptase-polymerase chain reaction on the oropharyngeal and nasopharyngeal swabs. Asymptomatic and symptomatic patients were compared in terms of maternal and perinatal outcomes. RESULTS: Our study population consisted of 20 asymptomatic and 41 symptomatic patients with laboratory-confirmed COVID-19. The rate of primary cesarean section was more than twice in the symptomatic group (51.2%) than that of the asymptomatic group (20%) (p=0.019). Both groups are quite similar in terms of maternal [respiratory support, COVID-19-related treatment, and intensive care unit (ICU) admission], perinatal (preterm delivery, preterm premature rupture of membrane, preeclampsia, and mode of delivery), and neonatal outcomes [birth weight, Apgar scores, neonatal ICU (NICU) admission]. The rate of total cesarean section in the asymptomatic group (75%) was statistically similar to the symptomatic group (83%) (p=0.464). The NICU admission rate was found to be similar in the asymptomatic (54.2%) and symptomatic groups (50%) (p=0.858). However, NICU admissions were more frequent in the symptomatic group due to respiratory distress (p=0.032). The breastfeeding rate is higher in the asymptomatic pregnant group as expected (p=0.015). Additionally, the ferritin level was significantly lower in the asymptomatic group (p=0.006). CONCLUSIONS: The rate of primary cesarean section is quite high in symptomatic patients with COVID-19. Additionally, the total cesarean section rate was extremely high in both groups. We expected more adverse outcomes in symptomatic patients; however, we found similar maternal, perinatal, and neonatal outcomes between both groups. Galenos Publishing 2022-03 2022-03-18 /pmc/articles/PMC8939442/ /pubmed/35306785 http://dx.doi.org/10.4274/MMJ.galenos.2022.47600 Text en © Copyright 2022 by the Istanbul Medeniyet University / Medeniyet Medical Journal published by Galenos Publishing House. https://creativecommons.org/licenses/by-nc/4.0/Licenced by Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
spellingShingle Original Article
VURAL, Tayfun
BAYRAKTAR, Burak
YILDIRIM KARACA, Suna
ODABAS, Ozan
YILMAZ, Nisel
SAMLIOGLU, Pınar
OZEREN, Mehmet
Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019
title Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019
title_full Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019
title_fullStr Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019
title_full_unstemmed Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019
title_short Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019
title_sort comparison of maternal, perinatal, and neonatal outcomes of asymptomatic and symptomatic pregnant women with coronavirus disease-2019
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939442/
https://www.ncbi.nlm.nih.gov/pubmed/35306785
http://dx.doi.org/10.4274/MMJ.galenos.2022.47600
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