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Clinical severity of RSV bronchiolitis

BACKGROUND: Studies comparing the severity of respiratory syncytial virus (RSV) bronchiolitis to other viruses are inconclusive. Our study aimed to compare the severity of bronchiolitis according to the virus. METHODS: Data were collected from 1152 infants under one year of age admitted to Children&...

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Autores principales: Hussain, Faris, Delgado Thompson, Margarita, Vick, David, West, Jack, Edwards, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939497/
https://www.ncbi.nlm.nih.gov/pubmed/35356804
http://dx.doi.org/10.1002/hsr2.543
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author Hussain, Faris
Delgado Thompson, Margarita
Vick, David
West, Jack
Edwards, Martin
author_facet Hussain, Faris
Delgado Thompson, Margarita
Vick, David
West, Jack
Edwards, Martin
author_sort Hussain, Faris
collection PubMed
description BACKGROUND: Studies comparing the severity of respiratory syncytial virus (RSV) bronchiolitis to other viruses are inconclusive. Our study aimed to compare the severity of bronchiolitis according to the virus. METHODS: Data were collected from 1152 infants under one year of age admitted to Children's hospital for Wales, over the winter months of 2014–2020. The cohort was divided based on the virus detected: RSV, RSV with another virus, or other virus. Using t tests and Fisher exact statistical test, the groups were compared based on length of hospital stay, admissions PICU/HDU, intubations, and need of nasogastric (NG) nutritional support. RESULTS: Fifty‐six percent throat swabs were RSV positive, 15% had RSV with another virus, and 29% had only another virus. Children positive for RSV had statistically longer hospital admissions and were more likely to need NG nutrition; however, there was no difference between number of PICU/HDU admissions or intubations. The RSV group and RSV with another virus group had no statistical differences.
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spelling pubmed-89394972022-03-29 Clinical severity of RSV bronchiolitis Hussain, Faris Delgado Thompson, Margarita Vick, David West, Jack Edwards, Martin Health Sci Rep Research Letter BACKGROUND: Studies comparing the severity of respiratory syncytial virus (RSV) bronchiolitis to other viruses are inconclusive. Our study aimed to compare the severity of bronchiolitis according to the virus. METHODS: Data were collected from 1152 infants under one year of age admitted to Children's hospital for Wales, over the winter months of 2014–2020. The cohort was divided based on the virus detected: RSV, RSV with another virus, or other virus. Using t tests and Fisher exact statistical test, the groups were compared based on length of hospital stay, admissions PICU/HDU, intubations, and need of nasogastric (NG) nutritional support. RESULTS: Fifty‐six percent throat swabs were RSV positive, 15% had RSV with another virus, and 29% had only another virus. Children positive for RSV had statistically longer hospital admissions and were more likely to need NG nutrition; however, there was no difference between number of PICU/HDU admissions or intubations. The RSV group and RSV with another virus group had no statistical differences. John Wiley and Sons Inc. 2022-03-22 /pmc/articles/PMC8939497/ /pubmed/35356804 http://dx.doi.org/10.1002/hsr2.543 Text en © 2022 The Authors. Health Science Reports published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Letter
Hussain, Faris
Delgado Thompson, Margarita
Vick, David
West, Jack
Edwards, Martin
Clinical severity of RSV bronchiolitis
title Clinical severity of RSV bronchiolitis
title_full Clinical severity of RSV bronchiolitis
title_fullStr Clinical severity of RSV bronchiolitis
title_full_unstemmed Clinical severity of RSV bronchiolitis
title_short Clinical severity of RSV bronchiolitis
title_sort clinical severity of rsv bronchiolitis
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939497/
https://www.ncbi.nlm.nih.gov/pubmed/35356804
http://dx.doi.org/10.1002/hsr2.543
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