Photoelectrochemical oxidation assisted air purifiers; perspective as potential tools to control indoor SARS-CoV-2 Exposure

Coronavirus diseases 2019 (COVID-19), a viral infection pandemic, arises due to easy human-to-human transmission of severe acute respiratory syndrome coronavirus (SARS-CoV-2). The SARS-CoV-2 causes severe respiratory disorders and other life-threatening diseases (during/post-infection) such as black mold disease, diabetes, cardiovascular, and neurological disorders/diseases. COVID-19 infection emerged challenging to control as SARS-CoV-2 transmits through respiratory droplets (> 10 µm size range), aerosols (< 5 µm), airborne, and particulate matter (PM(1.0) PM(2.5) and PM(10.0)). SARS-CoV-2 is more infective in indoor premises due to aerodynamics where droplets, aerosols, and PM(1.0/2.5/10.0) float for a longer time and distance leading to a higher probability of it entering upper and lower respiratory tracts. To avoid human-to-human transmission, it is essential to trap and destroy SARS-CoV-2 from the air and provide virus-free air that will significantly reduce indoor viral exposure concerns. In this process, an efficient nano-enable photoelectrochemical oxidation (PECO, a destructive approach to neutralize bio-organism) assisted air purification is undoubtedly a good technological choice. This technical perspective explores the role of PECO-assisted Air-Purifiers (i.e., Molekule as a focus example for proof-of-concept) to trap and destroy indoor microorganisms (bacteria and viruses including Coronaviruses), molds, and allergens, and other indoor air pollutants, such as volatile organic compounds (VOCs) and PM(1.0/2.5/10.0). It is observed through various standard and non-standard tests that stimuli-responsive nanomaterials coated filter technology traps and destroys microbial particles. Due to technological advancements according to premises requirements and high-performance desired outcomes, Molekule air purifiers, Air Pro Air -Rx, Air Mini, and Air Mini+, have received Food and Drug Administration (FDA) clearance as a Class II medical device for the destruction of bacteria and viruses.