Structures of the Omicron Spike trimer with ACE2 and an anti-Omicron antibody

The SARS-CoV-2 Omicron variant has become the dominant infective strain. We report the structures of the Omicron spike trimer on its own or in complex with ACE2 or an anti-Omicron antibody. Most Omicron mutations are located on the surface of the spike protein, which change binding epitopes to many...

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Detalles Bibliográficos
Autores principales: Yin, Wanchao, Xu, Youwei, Xu, Peiyu, Cao, Xiaodan, Wu, Canrong, Gu, Chunyin, He, Xinheng, Wang, Xiaoxi, Huang, Sijie, Yuan, Qingning, Wu, Kai, Hu, Wen, Huang, Zifu, Liu, Jia, Wang, Zongda, Jia, Fangfang, Xia, Kaiwen, Liu, Peipei, Wang, Xueping, Song, Bin, Zheng, Jie, Jiang, Hualiang, Cheng, Xi, Jiang, Yi, Deng, Su-Jun, Xu, H. Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939775/
https://www.ncbi.nlm.nih.gov/pubmed/35133176
http://dx.doi.org/10.1126/science.abn8863

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