Increased yield of AP-3 by inactivation of asm25 in Actinosynnema pretiosum ssp. auranticum ATCC 31565

Asamitocins are maytansinoids produced by Actinosynnema pretiosum ssp. auranticum ATCC 31565 (A. pretiosum ATCC 31565), which have a structure similar to that of maytansine, therefore serving as a precursor of maytansine in the development of antibody-drug conjugates (ADCs). Currently, there are mor...

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Detalles Bibliográficos
Autores principales: Cheng, Hong, Xiong, Guoqing, Li, Yi, Zhu, Jiaqi, Xiong, Xianghua, Wang, Qingyang, Zhang, Liancheng, Dong, Haolong, Zhu, Chen, Liu, Gang, Chen, Huipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939807/
https://www.ncbi.nlm.nih.gov/pubmed/35316825
http://dx.doi.org/10.1371/journal.pone.0265517

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