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Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

Retinitis Pigmentosa (RP) is a progressive, debilitating visual disorder caused by mutations in a diverse set of genes. In both humans with RP and mouse models of RP, rod photoreceptor dysfunction leads to loss of night vision, and is followed by secondary cone photoreceptor dysfunction and degenera...

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Detalles Bibliográficos
Autores principales: Amamoto, Ryoji, Wallick, Grace K, Cepko, Constance L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940176/
https://www.ncbi.nlm.nih.gov/pubmed/35315776
http://dx.doi.org/10.7554/eLife.76389