Cargando…

ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood–Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI

Promoting blood–spinal cord barrier (BSCB) repair at the early stage plays a crucial role in treatment of spinal cord injury (SCI). Excessive activation of autophagy can prevent recovery of BSCB after SCI. Basic fibroblast growth factor (bFGF) has been shown to promote BSCB repair and locomotor func...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Renkan, Xie, Ling, Wu, Fangfang, Xu, Ji, Lu, Leilei, Cao, Lin, Li, Lei, Meng, Weiyang, Zhang, Hongyu, Shao, Chuxiao, Li, Xiaokun, Chen, Daqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940228/ https://www.ncbi.nlm.nih.gov/pubmed/35330841 http://dx.doi.org/10.3389/fphar.2022.828896

Ejemplares similares

Hypoxia response element-directed expression of bFGF in dental pulp stem cells improve the hypoxic environment by targeting pericytes in SCI rats
por: Zhu, Sipin, et al.
Publicado: (2021)

Platelet derived growth factor promotes the recovery of traumatic brain injury by inhibiting endoplasmic reticulum stress and autophagy-mediated pyroptosis
por: Wu, Fangfang, et al.
Publicado: (2022)

The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals
por: Ye, Libing, et al.
Publicado: (2015)

Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells
Publicado: (1994)

Repair of spinal cord injury by implantation of bFGF-incorporated HEMA-MOETACL hydrogel in rats
por: Chen, Bo, et al.
Publicado: (2015)

Stimulation of wound healing using bioinspired hydrogels with basic fibroblast growth factor (bFGF)
por: Zhang, Xiaoyu, et al.
Publicado: (2018)

Thermosensitive heparin‐poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury
por: Hu, Xiaoli, et al.
Publicado: (2020)

Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury
por: Albashari, Abdullkhaleg, et al.
Publicado: (2020)

Expression of bFGF and VEGF in brain astrocytoma.
por: Shim, J. W., et al.
Publicado: (1996)

bFGF attenuates endoplasmic reticulum stress and mitochondrial injury on myocardial ischaemia/reperfusion via activation of PI3K/Akt/ERK1/2 pathway
por: Wang, Zhouguang, et al.
Publicado: (2015)

MMP-sensitive PEG hydrogel modified with RGD promotes bFGF, VEGF and EPC-mediated angiogenesis
por: Ouyang, Liu, et al.
Publicado: (2019)

Delivery of bFGF for Tissue Engineering by Tethering to the ECM
por: Suttinont, Chawapun, et al.
Publicado: (2015)

Biomaterial-Based bFGF Delivery for Nerve Repair
por: Huang, Qinying, et al.
Publicado: (2023)

Dual Delivery of NGF and bFGF Coacervater Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Schwann Cells Apoptosis
por: Li, Rui, et al.
Publicado: (2017)

Erratum to “Inhibition of Endoplasmic Reticulum Stress is Involved in the Neuroprotective Effect of bFGF in the 6-OHDA-Induced Parkinson’s Disease Model”
por: Cai, Pingtao, et al.
Publicado: (2023)

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate
Publicado: (1992)

Intramyocardial delivery of bFGF with a biodegradable and thermosensitive hydrogel improves angiogenesis and cardio-protection in infarcted myocardium
por: Zhu, Hongling, et al.
Publicado: (2017)

bFGF and collagen matrix hydrogel attenuates burn wound inflammation through activation of ERK and TRK pathway
por: Chakrabarti, Srijita, et al.
Publicado: (2021)

Ghrelin Ameliorates Traumatic Brain Injury by Down-Regulating bFGF and FGF-BP
por: Shao, Xuefei, et al.
Publicado: (2018)

The Quantitative Analysis of bFGF and VEGF by ELISA in Human Meningiomas
por: Denizot, Yves, et al.
Publicado: (2006)

The Regenerative Potential of bFGF in Dental Pulp Repair and Regeneration
por: Liu, Keyue, et al.
Publicado: (2021)

bFGF Promotes the Migration of Human Dermal Fibroblasts under Diabetic Conditions through Reactive Oxygen Species Production via the PI3K/Akt-Rac1- JNK Pathways
por: Shi, Hongxue, et al.
Publicado: (2015)

Effects of Transplanted Heparin-Poloxamer Hydrogel Combining Dental Pulp Stem Cells and bFGF on Spinal Cord Injury Repair
por: Luo, Lihua, et al.
Publicado: (2018)

bFGF alleviates diabetes-associated endothelial impairment by downregulating inflammation via S-nitrosylation pathway
por: Chen, Gen, et al.
Publicado: (2021)

Effect of bFGF and fibroblasts combined with hyaluronic acid-based hydrogels on soft tissue augmentation: an experimental study in rats
por: Lee, Su Yeon, et al.
Publicado: (2019)

Heparin-based coacervate of bFGF facilitates peripheral nerve regeneration by inhibiting endoplasmic reticulum stress following sciatic nerve injury
por: Li, Rui, et al.
Publicado: (2017)

Construction of a human monoclonal antibody against bFGF for suppression of NSCLC
por: Wang, Sheng, et al.
Publicado: (2018)

Notch Signaling Pathway Is Involved in bFGF-Induced Corneal Lymphangiogenesis and Hemangiogenesis
por: Xie, Fang, et al.
Publicado: (2019)

Myoprotective effects of bFGF on skeletal muscle injury in pressure-related deep tissue injury in rats
por: Shi, Hongxue, et al.
Publicado: (2016)

High-Efficiency Expression of TAT-bFGF Fusion Protein in Escherichia coli and the Effect on Hypertrophic Scar Tissue
por: Jia, Xuechao, et al.
Publicado: (2015)

Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells
por: Chengye, Wang, et al.
Publicado: (2017)

Lysophosphatidic acid and bFGF control different modes in proliferating myoblasts
Publicado: (1996)

VEGF and bFGF gene polymorphisms in Polish patients with B-CLL
por: Wróbel, Tomasz, et al.
Publicado: (2013)

VEGF and bFGF Gene Polymorphisms in Patients with Non-Hodgkin's Lymphoma
por: Wróbel, Tomasz, et al.
Publicado: (2013)

Multifunctional Nanocomposite Films for Synergistic Delivery of bFGF and BMP-2
por: Qi, Wei, et al.
Publicado: (2017)

The repair and autophagy mechanisms of hypoxia‐regulated bFGF‐modified primary embryonic neural stem cells in spinal cord injury
por: Zhu, Sipin, et al.
Publicado: (2020)

Upregulated insulin receptor tyrosine kinase substrate promotes the proliferation of colorectal cancer cells via the bFGF/AKT signaling pathway
por: Wang, Song, et al.
Publicado: (2020)

bFGF promotes Sca-1(+) cardiac stem cell migration through activation of the PI3K/Akt pathway
por: Ling, Lin, et al.
Publicado: (2018)

The correlation between ultrasonographic features, bFGF, and the local invasiveness of thyroid papillary carcinoma
por: Jia, Zhi-Ying, et al.
Publicado: (2020)

Thermo-sensitive hydrogels combined with decellularised matrix deliver bFGF for the functional recovery of rats after a spinal cord injury
por: Xu, He-Lin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rvlamgl0miuj6u34v58lmjj943