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Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema

There is limited information on canine spinal epidural empyema (SEE). The aim of this multicenter retrospective study is to describe the clinical presentation and outcome of dogs undergoing spinal surgery or conservative management for SEE. Forty-one dogs met the inclusion criteria; the SEE was trea...

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Autores principales: Laws, Emma J., Sánchez, Lluís, Beltran, Elsa, Domínguez, Elisabet, Ekiri, Abel B., Brocal, Josep, De Risio, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940254/
https://www.ncbi.nlm.nih.gov/pubmed/35330611
http://dx.doi.org/10.3389/fvets.2022.813316
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author Laws, Emma J.
Sánchez, Lluís
Beltran, Elsa
Domínguez, Elisabet
Ekiri, Abel B.
Brocal, Josep
De Risio, Luisa
author_facet Laws, Emma J.
Sánchez, Lluís
Beltran, Elsa
Domínguez, Elisabet
Ekiri, Abel B.
Brocal, Josep
De Risio, Luisa
author_sort Laws, Emma J.
collection PubMed
description There is limited information on canine spinal epidural empyema (SEE). The aim of this multicenter retrospective study is to describe the clinical presentation and outcome of dogs undergoing spinal surgery or conservative management for SEE. Forty-one dogs met the inclusion criteria; the SEE was treated surgically in 17 dogs and conservatively in 24 dogs. Two dogs underwent spinal surgery after failure of conservative management, meaning that 19 dogs in total had spinal surgery. Long-term (i.e., >6 months) follow-up was available in 35 dogs (19 conservatively treated and 16 surgically treated dogs). Recovery to a functional pet status was achieved in 15/19 (78.9%) conservatively treated and 12/16 (75%) surgically treated dogs. There was no significant difference (p = 1.000) in long-term outcome between conservatively and surgically treated dogs (78.9 and 75%, respectively). However, significantly more surgically treated dogs were non-ambulatory at presentation (9/17 vs. 5/24, p = 0.048) compared with conservatively treated dogs. This study suggests that conservative treatment may be appropriate for dogs with SEE that are ambulatory at presentation and that surgically treated dogs generally have good outcomes. Age may be a negative prognostic indicator as dogs with poor long-term outcomes were significantly older than dogs with a good long-term outcome (p = 0.048). A larger prospective randomized study may provide further insight on treatment and outcome of SEE in dogs.
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spelling pubmed-89402542022-03-23 Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema Laws, Emma J. Sánchez, Lluís Beltran, Elsa Domínguez, Elisabet Ekiri, Abel B. Brocal, Josep De Risio, Luisa Front Vet Sci Veterinary Science There is limited information on canine spinal epidural empyema (SEE). The aim of this multicenter retrospective study is to describe the clinical presentation and outcome of dogs undergoing spinal surgery or conservative management for SEE. Forty-one dogs met the inclusion criteria; the SEE was treated surgically in 17 dogs and conservatively in 24 dogs. Two dogs underwent spinal surgery after failure of conservative management, meaning that 19 dogs in total had spinal surgery. Long-term (i.e., >6 months) follow-up was available in 35 dogs (19 conservatively treated and 16 surgically treated dogs). Recovery to a functional pet status was achieved in 15/19 (78.9%) conservatively treated and 12/16 (75%) surgically treated dogs. There was no significant difference (p = 1.000) in long-term outcome between conservatively and surgically treated dogs (78.9 and 75%, respectively). However, significantly more surgically treated dogs were non-ambulatory at presentation (9/17 vs. 5/24, p = 0.048) compared with conservatively treated dogs. This study suggests that conservative treatment may be appropriate for dogs with SEE that are ambulatory at presentation and that surgically treated dogs generally have good outcomes. Age may be a negative prognostic indicator as dogs with poor long-term outcomes were significantly older than dogs with a good long-term outcome (p = 0.048). A larger prospective randomized study may provide further insight on treatment and outcome of SEE in dogs. Frontiers Media S.A. 2022-03-07 /pmc/articles/PMC8940254/ /pubmed/35330611 http://dx.doi.org/10.3389/fvets.2022.813316 Text en Copyright © 2022 Laws, Sánchez, Beltran, Domínguez, Ekiri, Brocal and De Risio. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Laws, Emma J.
Sánchez, Lluís
Beltran, Elsa
Domínguez, Elisabet
Ekiri, Abel B.
Brocal, Josep
De Risio, Luisa
Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema
title Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema
title_full Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema
title_fullStr Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema
title_full_unstemmed Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema
title_short Multicenter Study of Clinical Presentation, Treatment, and Outcome in 41 Dogs With Spinal Epidural Empyema
title_sort multicenter study of clinical presentation, treatment, and outcome in 41 dogs with spinal epidural empyema
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940254/
https://www.ncbi.nlm.nih.gov/pubmed/35330611
http://dx.doi.org/10.3389/fvets.2022.813316
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