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Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties

Sulfation pattern and molecular weight (MW) play a key role in the biological actions of sulfated glycans. Besides anticoagulant effects, certain sulfated glycans can also exhibit anti-SARS-CoV-2 properties. To develop a more selective antiviral carbohydrate, an efficient strategy to separate these...

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Detalles Bibliográficos
Autores principales: Kim, Seon Beom, Zoepfl, Mary, Samanta, Priyanka, Zhang, Fuming, Xia, Ke, Thara, Reena, Linhardt, Robert J., Doerksen, Robert J., McVoy, Michael A., Pomin, Vitor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940257/
https://www.ncbi.nlm.nih.gov/pubmed/35337800
http://dx.doi.org/10.1016/j.jbc.2022.101856

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