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Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties
Sulfation pattern and molecular weight (MW) play a key role in the biological actions of sulfated glycans. Besides anticoagulant effects, certain sulfated glycans can also exhibit anti-SARS-CoV-2 properties. To develop a more selective antiviral carbohydrate, an efficient strategy to separate these...
Autores principales: | Kim, Seon Beom, Zoepfl, Mary, Samanta, Priyanka, Zhang, Fuming, Xia, Ke, Thara, Reena, Linhardt, Robert J., Doerksen, Robert J., McVoy, Michael A., Pomin, Vitor H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940257/ https://www.ncbi.nlm.nih.gov/pubmed/35337800 http://dx.doi.org/10.1016/j.jbc.2022.101856 |
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