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Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration

Low back pain, mainly caused by intervertebral disc degeneration (IVDD), is a common health problem; however, current surgical treatments are less than satisfactory. Thus, it is essential to develop novel non-invasive surgical methods for IVDD treatment. Here, we describe a therapeutic strategy to i...

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Detalles Bibliográficos
Autores principales: Luo, Liwen, Gong, Junfeng, Wang, Zhouguang, Liu, Yao, Cao, Jiaming, Qin, Jinghao, Zuo, Rui, Zhang, Hongyu, Wang, Shuai, Zhao, Ping, Yang, Di, Zhang, Mengjie, Wang, Yanqiu, Zhang, Junfeng, Zhou, Yue, Li, Changqing, Ni, Bing, Tian, Zhiqiang, Liu, MingHan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940768/
https://www.ncbi.nlm.nih.gov/pubmed/35386360
http://dx.doi.org/10.1016/j.bioactmat.2021.12.007