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P2Y1 agonist HIC in combination with androgen receptor inhibitor abiraterone acetate impairs cell growth of prostate cancer

P2Y receptors belong to the large superfamily of G-protein-coupled receptors and play a crucial role in cell death and survival. P2Y1 receptor has been identified as a marker for prostate cancer (PCa). A previously unveiled selective P2Y1 receptor agonist, the indoline-derived HIC (1-(1-((2-hydroxy-...

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Detalles Bibliográficos
Autores principales:	Le, Hien Thi Thu, Murugesan, Akshaya, Candeias, Nuno R., Ramesh, Thiyagarajan, Yli-Harja, Olli, Kandhavelu, Meenakshisundaram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940814/ https://www.ncbi.nlm.nih.gov/pubmed/35129730 http://dx.doi.org/10.1007/s10495-022-01716-1

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