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Interleukin-6 as surrogate marker for imaging-based hypoxia dynamics in patients with head-and-neck cancers undergoing definitive chemoradiation—results from a prospective pilot trial

PURPOSE: Intratumoral hypoxia increases resistance of head-and-neck squamous cell carcinoma (HNSCC) to radiotherapy. [(18)F]FMISO PET imaging enables noninvasive hypoxia monitoring, though requiring complex logistical efforts. We investigated the role of plasma interleukin-6 (IL-6) as potential surr...

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Detalles Bibliográficos
Autores principales:	Rühle, Alexander, Wiedenmann, Nicole, Fennell, Jamina T., Mix, Michael, Ruf, Juri, Stoian, Raluca, Thomsen, Andreas R., Vaupel, Peter, Baltas, Dimos, Grosu, Anca-L., Nicolay, Nils H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940848/ https://www.ncbi.nlm.nih.gov/pubmed/34773163 http://dx.doi.org/10.1007/s00259-021-05602-x

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