YTHDF1 upregulation mediates hypoxia-dependent breast cancer growth and metastasis through regulating PKM2 to affect glycolysis

N6-methyladenosine modification is the most common RNA modification mechanism in mammals. YTHDF1, a m(6)A reader, can recognize the m(6)A of mRNAs to facilitate the interaction with the mRNA ribosome assembly and recruitment of translation initiators to promote translation. From a clinical perspecti...

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Detalles Bibliográficos
Autores principales: Yao, Xuemei, Li, Wei, Li, Liqi, Li, Menghuan, Zhao, Youbo, Fang, De, Zeng, Xiaohua, Luo, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940925/
https://www.ncbi.nlm.nih.gov/pubmed/35319018
http://dx.doi.org/10.1038/s41419-022-04711-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940925/
https://www.ncbi.nlm.nih.gov/pubmed/35319018
http://dx.doi.org/10.1038/s41419-022-04711-1

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