Cargando…

Pharmacokinetics, Safety, Efficacy, and Biomarker Profiles During Nemolizumab Treatment of Atopic Dermatitis in Adolescents

INTRODUCTION: Nemolizumab, a new monoclonal antibody that targets the receptor alpha of the neuroimmune cytokine interleukin-31 (IL-31), has shown efficacy in atopic dermatitis (AD) in adults. This study evaluated the pharmacokinetics (PK) and safety of nemolizumab in adolescents with moderate to se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sidbury, Robert, Alpizar, Sady, Laquer, Vivian, Dhawan, Sunil, Abramovits, William, Loprete, Luca, Krishnaswamy, Jayendar Kumar, Ahmad, Faiz, Jabbar-Lopez, Zarif, Piketty, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941010/ https://www.ncbi.nlm.nih.gov/pubmed/35088348 http://dx.doi.org/10.1007/s13555-021-00678-7

Ejemplares similares

Modulation of Neuroimmune and Epithelial Dysregulation in Patients With Moderate to Severe Prurigo Nodularis Treated With Nemolizumab
por: Deng, Junwen, et al.
Publicado: (2023)

Advances in understanding and managing atopic dermatitis
por: Barton, Michael, et al.
Publicado: (2015)

Safety and Efficacy of Nemolizumab for Atopic Dermatitis With Pruritus: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials
por: Liang, Junqin, et al.
Publicado: (2022)

Nemolizumab efficacy in prurigo nodularis: onset of action on itch and sleep disturbances
por: Ständer, S., et al.
Publicado: (2022)

Nemolizumab in moderate to severe atopic dermatitis: An exploratory analysis of work productivity and activity impairment in a randomized phase II study
por: Mihara, Ryosuke, et al.
Publicado: (2019)

Assessing Response in Atopic Dermatitis: A Systematic Review of the Psychometric Performance of Measures Used in HTAs and Clinical Trials
por: Penton, Hannah, et al.
Publicado: (2023)

Nemolizumab Improves Patient-Reported Symptoms of Atopic Dermatitis with Pruritus: Post Hoc Analysis of a Japanese Phase III Randomized Controlled Trial
por: Kabashima, Kenji, et al.
Publicado: (2023)

Novel systemic therapies in atopic dermatitis: what do we need to fulfil the promise of a treatment revolution?
por: Alexander, Helen, et al.
Publicado: (2019)

Nemolizumab plus topical agents in patients with atopic dermatitis (AD) and moderate‐to‐severe pruritus provide improvement in pruritus and signs of AD for up to 68 weeks: results from two phase III, long‐term studies
por: Kabashima, K., et al.
Publicado: (2021)

Is Dupilumab as Effective in Intrinsic Atopic Dermatitis as It Is in Extrinsic Atopic Dermatitis?
por: Gelato, Federica, et al.
Publicado: (2023)

The infectious complications of atopic dermatitis
por: Wang, Vivian, et al.
Publicado: (2021)

Pharmacokinetics, pharmacodynamics, and exposure–efficacy of dupilumab in adults with atopic dermatitis
por: Kamal, Mohamed A., et al.
Publicado: (2022)

Safety of Lebrikizumab in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: An Integrated Analysis of Eight Clinical Trials
por: Stein Gold, Linda, et al.
Publicado: (2023)

Systemic immunomodulatory treatments for atopic dermatitis: protocol for a systematic review with network meta-analysis
por: Drucker, Aaron Mark, et al.
Publicado: (2018)

Conceptual Model to Illustrate the Symptom Experience and Humanistic Burden Associated With Atopic Dermatitis in Adults and Adolescents
por: Grant, Laura, et al.
Publicado: (2019)

Population Pharmacokinetics of Abrocitinib in Healthy Individuals and Patients with Psoriasis or Atopic Dermatitis
por: Wojciechowski, Jessica, et al.
Publicado: (2022)

Population Pharmacokinetics of Tralokinumab in Adult Subjects With Moderate to Severe Atopic Dermatitis
por: Soehoel, Anders, et al.
Publicado: (2022)

Atopic dermatitis
por: Werfel, Thomas
Publicado: (2011)

Atopic dermatitis
por: Watson, Wade, et al.
Publicado: (2011)

Atopic dermatitis
por: Kapur, Sandeep, et al.
Publicado: (2018)

Atopic dermatitis
por: Galli, Elena, et al.
Publicado: (2020)

Severe atopic dermatitis and dupilumab
por: Bernardo, Wanderley, et al.
Publicado: (2023)

An explanatory sequential mixed-methods design to establish thresholds of within-individual meaningful change on a sleep disturbance numerical rating scale score in atopic dermatitis
por: Dias-Barbosa, Carla, et al.
Publicado: (2022)

Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
por: Gaspar, Neide Kalil, et al.
Publicado: (2016)

Different phenotypes and factors associated with atopic dermatitis in the young adult Singaporean Chinese population: A cross-sectional study
por: Matta, Sri Anusha, et al.
Publicado: (2019)

Therapeutic Potential of Lebrikizumab in the Treatment of Atopic Dermatitis
por: Loh, Tiffany Y, et al.
Publicado: (2020)

Correction to: Population Pharmacokinetics of Abrocitinib in Healthy Individuals and Patients with Psoriasis or Atopic Dermatitis
por: Wojciechowski, Jessica, et al.
Publicado: (2022)

Psychometric validation and responder definition of the sleep disturbance numerical rating scale in moderate‐to‐severe atopic dermatitis
por: Puelles, J., et al.
Publicado: (2021)

Overview of atopic dermatitis
por: Kim, Kyu Han
Publicado: (2013)

Atopic dermatitis in adolescence
por: Ricci, Giampaolo, et al.
Publicado: (2011)

Prevention of atopic dermatitis
por: Williams, Hywel C., et al.
Publicado: (2012)

Autoallergy in atopic dermatitis
por: Hradetzky, Susanne, et al.
Publicado: (2015)

Psoriasis and Atopic Dermatitis
por: Griffiths, Christopher E. M., et al.
Publicado: (2017)

Microbiome in atopic dermatitis
por: Wollina, Uwe
Publicado: (2017)

Atopic Dermatitis and Comorbidity
por: Bekić, Sanja, et al.
Publicado: (2020)

Autoimmunity (or Not) in Atopic Dermatitis
por: Roesner, Lennart M., et al.
Publicado: (2019)

The exposome in atopic dermatitis
por: Stefanovic, Nicholas, et al.
Publicado: (2019)

Dupilumab for atopic dermatitis
Publicado: (2019)

Crisaborole for atopic dermatitis
Publicado: (2019)

Prevention of Atopic Dermatitis
por: WILLIAMS, Hywel C., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pg07km3409om8n0engvp0l8208