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Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD

Autism spectrum disorder (ASD) is a neurodevelopmental disease featuring social interaction deficits and repetitive/stereotyped behaviours; the prevalence of this disorder has continuously increased. Progranulin (PGRN) is a neurotrophic factor that promotes neuronal survival and differentiation. How...

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Detalles Bibliográficos
Autores principales:	Wang, Lili, Chen, Jianhui, Hu, Yuling, Liao, Ailing, Zheng, Wenxia, Wang, Xiaoqing, Lan, Junying, Shen, Jingjing, Wang, Shali, Yang, Feng, Wang, Yan, Li, Yingbo, Chen, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941112/ https://www.ncbi.nlm.nih.gov/pubmed/35318322 http://dx.doi.org/10.1038/s41398-022-01875-4

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