Dynamical modeling of miR-34a, miR-449a, and miR-16 reveals numerous DDR signaling pathways regulating senescence, autophagy, and apoptosis in HeLa cells

Transfection of tumor suppressor miRNAs such as miR-34a, miR-449a, and miR-16 with DNA damage can regulate apoptosis and senescence in cancer cells. miR-16 has been shown to influence autophagy in cervical cancer. However, the function of miR-34a and miR-449a in autophagy remains unknown. The functi...

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Detalles Bibliográficos
Autores principales: Gupta, Shantanu, Panda, Pritam Kumar, Hashimoto, Ronaldo F., Samal, Shailesh Kumar, Mishra, Suman, Verma, Suresh Kr., Mishra, Yogendra Kumar, Ahuja, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941124/
https://www.ncbi.nlm.nih.gov/pubmed/35318393
http://dx.doi.org/10.1038/s41598-022-08900-y

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