Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease

We describe a rare case of a patient with mixed connective tissue disease maintained on chronic oral corticosteroids, who was hospitalized on five occasions over five consecutive months due to persistent relapsing neutrophilic meningitis caused by Nocardia asteroides. Immunosuppression due to the ch...

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Autores principales: Albornoz, M. Anthony, Threlfall, Erin K., Baldassari, Michael Philip, Livornese, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941153/
https://www.ncbi.nlm.nih.gov/pubmed/35340754
http://dx.doi.org/10.1016/j.idcr.2022.e01473
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author Albornoz, M. Anthony
Threlfall, Erin K.
Baldassari, Michael Philip
Livornese, Lawrence J.
author_facet Albornoz, M. Anthony
Threlfall, Erin K.
Baldassari, Michael Philip
Livornese, Lawrence J.
author_sort Albornoz, M. Anthony
collection PubMed
description We describe a rare case of a patient with mixed connective tissue disease maintained on chronic oral corticosteroids, who was hospitalized on five occasions over five consecutive months due to persistent relapsing neutrophilic meningitis caused by Nocardia asteroides. Immunosuppression due to the chronic use of corticosteroids was identified as the underlying mechanism of susceptibility. Our report highlights the challenges associated with systemic Nocardiosis, particularly in the immunocompromised host.
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spelling pubmed-89411532022-03-24 Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease Albornoz, M. Anthony Threlfall, Erin K. Baldassari, Michael Philip Livornese, Lawrence J. IDCases Case Report We describe a rare case of a patient with mixed connective tissue disease maintained on chronic oral corticosteroids, who was hospitalized on five occasions over five consecutive months due to persistent relapsing neutrophilic meningitis caused by Nocardia asteroides. Immunosuppression due to the chronic use of corticosteroids was identified as the underlying mechanism of susceptibility. Our report highlights the challenges associated with systemic Nocardiosis, particularly in the immunocompromised host. Elsevier 2022-03-09 /pmc/articles/PMC8941153/ /pubmed/35340754 http://dx.doi.org/10.1016/j.idcr.2022.e01473 Text en © 2022 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Albornoz, M. Anthony
Threlfall, Erin K.
Baldassari, Michael Philip
Livornese, Lawrence J.
Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease
title Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease
title_full Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease
title_fullStr Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease
title_full_unstemmed Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease
title_short Chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease
title_sort chronic relapsing neutrophilic meningitis as the sole manifestation of nocardiosis in a patient with mixed connective tissue disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941153/
https://www.ncbi.nlm.nih.gov/pubmed/35340754
http://dx.doi.org/10.1016/j.idcr.2022.e01473
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