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Tissue-specific alternative splicing separates the catalytic and cell signaling functions of human leucyl-tRNA synthetase

The aminoacyl-tRNA synthetases are an ancient and ubiquitous component of all life. Many eukaryotic synthetases balance their essential function, preparing aminoacyl-tRNA for use in mRNA translation, with diverse roles in cell signaling. Herein, we use long-read sequencing to discover a leukocyte-sp...

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Detalles Bibliográficos
Autores principales:	Baymiller, Max, Nordick, Benjamin, Forsyth, Connor M., Martinis, Susan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941210/ https://www.ncbi.nlm.nih.gov/pubmed/35202654 http://dx.doi.org/10.1016/j.jbc.2022.101757

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