Quantitative Metaproteomics and Activity-based Protein Profiling of Patient Fecal Microbiome Identifies Host and Microbial Serine-type Endopeptidase Activity Associated With Ulcerative Colitis

The gut microbiota plays an important yet incompletely understood role in the induction and propagation of ulcerative colitis (UC). Organism-level efforts to identify UC-associated microbes have revealed the importance of community structure, but less is known about the molecular effectors of diseas...

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Detalles Bibliográficos
Autores principales: Thuy-Boun, Peter S., Wang, Ana Y., Crissien-Martinez, Ana, Xu, Janice H., Chatterjee, Sandip, Stupp, Gregory S., Su, Andrew I., Coyle, Walter J., Wolan, Dennis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941213/
https://www.ncbi.nlm.nih.gov/pubmed/35033677
http://dx.doi.org/10.1016/j.mcpro.2022.100197

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