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Moderate l-lactate administration suppresses adipose tissue macrophage M1 polarization to alleviate obesity-associated insulin resistance

As a crucial metabolic intermediate, l-lactate is involved in redox balance, energy balance, and acid–base balance in organisms. Moderate exercise training transiently elevates plasma l-lactate levels and ameliorates obesity-associated type 2 diabetes. However, whether moderate l-lactate administrat...

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Detalles Bibliográficos
Autores principales: Cai, Hao, Wang, Xin, Zhang, Zhixin, Chen, Juan, Wang, Fangbin, Wang, Lu, Liu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941214/
https://www.ncbi.nlm.nih.gov/pubmed/35218776
http://dx.doi.org/10.1016/j.jbc.2022.101768

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