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Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation

BACKGROUND: Intimal hyperplasia (IH) remains a major limitation in the long-term success of any type of revascularisation. IH is due to vascular smooth muscle cell (VSMC) dedifferentiation, proliferation and migration. The gasotransmitter Hydrogen Sulfide (H(2)S), mainly produced in blood vessels by...

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Detalles Bibliográficos
Autores principales: Macabrey, Diane, Longchamp, Alban, MacArthur, Michael R., Lambelet, Martine, Urfer, Severine, Deglise, Sebastien, Allagnat, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941337/
https://www.ncbi.nlm.nih.gov/pubmed/35334307
http://dx.doi.org/10.1016/j.ebiom.2022.103954