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Cross-country evidence on the role of national governance in boosting COVID-19 vaccination

BACKGROUND: Frequent mutations of the COVID-19 virus, such as the Delta and Omicron variants, have prolonged the pandemic. Rich countries have approved the booster shots (3(rd) doses) of vaccine, but this causes further delay of vaccination in developing countries. This raises the risk of further mu...

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Autores principales: Aida, Takeshi, Shoji, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941364/
https://www.ncbi.nlm.nih.gov/pubmed/35321676
http://dx.doi.org/10.1186/s12889-022-12985-5
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author Aida, Takeshi
Shoji, Masahiro
author_facet Aida, Takeshi
Shoji, Masahiro
author_sort Aida, Takeshi
collection PubMed
description BACKGROUND: Frequent mutations of the COVID-19 virus, such as the Delta and Omicron variants, have prolonged the pandemic. Rich countries have approved the booster shots (3(rd) doses) of vaccine, but this causes further delay of vaccination in developing countries. This raises the risk of further mutations, which may lower the efficacy of currently available vaccines. As herd immunity by universal vaccination is essential to end the pandemic, the COVID-19 Vaccine Global Access (COVAX) facility has been established to provide developing countries with subsidized vaccines. However, a critical issue is that the developing countries also need to effectively deploy vaccines to citizens. Although this argument suggests positive effects of good national governance on vaccination coverage, to the best of our knowledge, there is no cross-country evidence on the role of national governance in increasing the coverage of COVID-19 vaccines among citizens. The goal of this study was to examine the association between the national governance and vaccination coverage among developing countries. METHODS: Using cross-country data, an ordinary least squares regression was conducted to examine the association between the national governance index and three outcomes: (1) the number of days until the administration of the first dose in the country since December 2019, (2) the number of doses per 100 citizens as of the end of July 2021, and (3) the selection of approved vaccine manufacturers. The results were compared between the model including all countries and the model excluding the member countries of Organisation for Economic Co-operation and Development (OECD). RESULTS: A one standard deviation increase in the national governance index was associated with 9.1 days (95%CI: -15.76, -2.43) earlier administration of vaccines in the country, and a 12.1 dose increase (95%CI: 4.76, 19.34) per 100 citizens. These associations were larger in the non-OECD sample. The results also indicated the role of governance in the selection of the administered vaccines. CONCLUSION: The provision of subsidized vaccines alone is not sufficient to control the spread of infection in developing countries; logistical and administrative support should also be offered, especially in countries with poor governance. TRIAL REGISTRATION: Not applicable SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-022-12985-5.
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spelling pubmed-89413642022-03-23 Cross-country evidence on the role of national governance in boosting COVID-19 vaccination Aida, Takeshi Shoji, Masahiro BMC Public Health Research BACKGROUND: Frequent mutations of the COVID-19 virus, such as the Delta and Omicron variants, have prolonged the pandemic. Rich countries have approved the booster shots (3(rd) doses) of vaccine, but this causes further delay of vaccination in developing countries. This raises the risk of further mutations, which may lower the efficacy of currently available vaccines. As herd immunity by universal vaccination is essential to end the pandemic, the COVID-19 Vaccine Global Access (COVAX) facility has been established to provide developing countries with subsidized vaccines. However, a critical issue is that the developing countries also need to effectively deploy vaccines to citizens. Although this argument suggests positive effects of good national governance on vaccination coverage, to the best of our knowledge, there is no cross-country evidence on the role of national governance in increasing the coverage of COVID-19 vaccines among citizens. The goal of this study was to examine the association between the national governance and vaccination coverage among developing countries. METHODS: Using cross-country data, an ordinary least squares regression was conducted to examine the association between the national governance index and three outcomes: (1) the number of days until the administration of the first dose in the country since December 2019, (2) the number of doses per 100 citizens as of the end of July 2021, and (3) the selection of approved vaccine manufacturers. The results were compared between the model including all countries and the model excluding the member countries of Organisation for Economic Co-operation and Development (OECD). RESULTS: A one standard deviation increase in the national governance index was associated with 9.1 days (95%CI: -15.76, -2.43) earlier administration of vaccines in the country, and a 12.1 dose increase (95%CI: 4.76, 19.34) per 100 citizens. These associations were larger in the non-OECD sample. The results also indicated the role of governance in the selection of the administered vaccines. CONCLUSION: The provision of subsidized vaccines alone is not sufficient to control the spread of infection in developing countries; logistical and administrative support should also be offered, especially in countries with poor governance. TRIAL REGISTRATION: Not applicable SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-022-12985-5. BioMed Central 2022-03-23 /pmc/articles/PMC8941364/ /pubmed/35321676 http://dx.doi.org/10.1186/s12889-022-12985-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Aida, Takeshi
Shoji, Masahiro
Cross-country evidence on the role of national governance in boosting COVID-19 vaccination
title Cross-country evidence on the role of national governance in boosting COVID-19 vaccination
title_full Cross-country evidence on the role of national governance in boosting COVID-19 vaccination
title_fullStr Cross-country evidence on the role of national governance in boosting COVID-19 vaccination
title_full_unstemmed Cross-country evidence on the role of national governance in boosting COVID-19 vaccination
title_short Cross-country evidence on the role of national governance in boosting COVID-19 vaccination
title_sort cross-country evidence on the role of national governance in boosting covid-19 vaccination
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941364/
https://www.ncbi.nlm.nih.gov/pubmed/35321676
http://dx.doi.org/10.1186/s12889-022-12985-5
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