Deletion of Y chromosome before allogeneic hematopoietic stem cell transplantation in male recipients with female donors

The graft-versus-leukemia (GVL) effect is one of the curative mechanisms of allogeneic hematopoietic stem cell transplantation (allo-HCT). H-Y antigens, which are encoded by Y chromosome, are important targets of the GVL effect. Thus, deletion of the Y chromosome (del[Y]) might cause the GVL effect...

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Detalles Bibliográficos
Autores principales: Tamaki, Masaharu, Kameda, Kazuaki, Kimura, Shun-ichi, Harada, Naonori, Uchida, Naoyuki, Doki, Noriko, Tanaka, Masatsugu, Ikegame, Kazuhiro, Sawa, Masashi, Katayama, Yuta, Miyakoshi, Shigesaburo, Ara, Takahide, Kanda, Junya, Onizuka, Makoto, Fukuda, Takahiro, Atsuta, Yoshiko, Kanda, Yoshinobu, Yakushijin, Kimikazu, Nakasone, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941451/
https://www.ncbi.nlm.nih.gov/pubmed/35108728
http://dx.doi.org/10.1182/bloodadvances.2021006456

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