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4-1BBL–containing leukemic extracellular vesicles promote immunosuppressive effector regulatory T cells

Chronic and acute myeloid leukemia evade immune system surveillance and induce immunosuppression by expanding proleukemic Foxp3(+) regulatory T cells (Tregs). High levels of immunosuppressive Tregs predict inferior response to chemotherapy, leukemia relapse, and shorter survival. However, mechanisms...

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Detalles Bibliográficos
Autores principales:	Swatler, Julian, Turos-Korgul, Laura, Brewinska-Olchowik, Marta, De Biasi, Sara, Dudka, Wioleta, Le, Bac Viet, Kominek, Agata, Cyranowski, Salwador, Pilanc, Paulina, Mohammadi, Elyas, Cysewski, Dominik, Kozlowska, Ewa, Grabowska-Pyrzewicz, Wioleta, Wojda, Urszula, Basak, Grzegorz, Mieczkowski, Jakub, Skorski, Tomasz, Cossarizza, Andrea, Piwocka, Katarzyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Immunobiology and Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941461/ https://www.ncbi.nlm.nih.gov/pubmed/35130345 http://dx.doi.org/10.1182/bloodadvances.2021006195

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