Telomerase deficiency reflects age-associated changes in CD4+ T cells

BACKGROUND: Amongst other systemic changes, aging leads to an immune dysfunction. On the molecular level, a hallmark of aging is telomere shortening. The functional relevance of telomerase, an enzyme capable of elongating telomeres in T cells upon antigen stimulation, is not fully understood. Studyi...

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Detalles Bibliográficos
Autores principales: Matthe, Diana M., Thoma, Oana-Maria, Sperka, Tobias, Neurath, Markus F., Waldner, Maximilian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941756/
https://www.ncbi.nlm.nih.gov/pubmed/35321714
http://dx.doi.org/10.1186/s12979-022-00273-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941756/
https://www.ncbi.nlm.nih.gov/pubmed/35321714
http://dx.doi.org/10.1186/s12979-022-00273-0

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