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Targeting the T-Cell Lymphoma Epigenome Induces Cell Death, Cancer Testes Antigens, Immune-Modulatory Signaling Pathways

The peripheral T-cell lymphomas (PTCL) could be considered the prototypical epigenetic disease. As a disease, they are uniquely sensitive to histone deacetylase (HDAC) and DNA methyltransferase (DNMT) inhibitors, both alone and in combination, are characterized by a host of mutations in epigenetic g...

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Detalles Bibliográficos
Autores principales:	Scotto, Luigi, Kinahan, Cristina, Douglass, Eugene, Deng, Changchun, Safari, Maryam, Casadei, Beatrice, Marchi, Enrica, Lue, Jennifer K., Montanari, Francesca, Falchi, Lorenzo, Qiao, Changhong, Renu, Nandakumar, Bates, Susan E., Califano, Andrea, O'Connor, Owen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2021
Materias:	Small Molecule Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941846/ https://www.ncbi.nlm.nih.gov/pubmed/34108263 http://dx.doi.org/10.1158/1535-7163.MCT-20-0377

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