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Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice

SARS-CoV-2 variants of concern (VoC) are impacting responses to the COVID-19 pandemic. Here, we utilized passive immunization using human convalescent plasma (HCP) obtained from a critically ill COVID-19 patient in the early pandemic to study the efficacy of polyclonal antibodies generated to ancest...

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Detalles Bibliográficos
Autores principales: Wong, Ting Y., Horspool, Alexander M., Russ, Brynnan P., Ye, Chengjin, Lee, Katherine S., Winters, Michael T., Bevere, Justin R., Miller, Olivia A., Rader, Nathaniel A., Cooper, Melissa, Kieffer, Theodore, Sourimant, Julien, Greninger, Alexander L., Plemper, Richard K., Denvir, James, Cyphert, Holly A., Barbier, Mariette, Torrelles, Jordi B., Martinez, Ivan, Martinez-Sobrido, Luis, Damron, F. Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941865/
https://www.ncbi.nlm.nih.gov/pubmed/35080423
http://dx.doi.org/10.1128/jvi.02184-21