Cargando…

Host Cellular RNA Helicases Regulate SARS-CoV-2 Infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the largest RNA genome, approximately 30 kb, among RNA viruses. The DDX DEAD box RNA helicase is a multifunctional protein involved in all aspects of RNA metabolism. Therefore, host RNA helicases may regulate and maintain such a large...

Descripción completa

Detalles Bibliográficos
Autor principal:	Ariumi, Yasuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941876/ https://www.ncbi.nlm.nih.gov/pubmed/35107372 http://dx.doi.org/10.1128/jvi.00002-22

Ejemplares similares

Spike Glycoprotein and Host Cell Determinants of SARS-CoV-2 Entry and Cytopathic Effects
por: Nguyen, Hanh T., et al.
Publicado: (2021)

Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV
por: Lokugamage, Kumari G., et al.
Publicado: (2020)

Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity
por: Essalmani, Rachid, et al.
Publicado: (2022)

Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease
por: Kreutzberger, Alex J. B., et al.
Publicado: (2021)

The Cellular Characterization of SARS-CoV-2 Spike Protein in Virus-Infected Cells Using the Receptor Binding Domain Binding Specific Human Monoclonal Antibodies
por: Chan, Conrad En-Zuo, et al.
Publicado: (2022)

SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog
por: Chen, Jiyao, et al.
Publicado: (2022)

SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation
por: Hörnich, Bojan F., et al.
Publicado: (2021)

Neuromasts and Olfactory Organs of Zebrafish Larvae Represent Possible Sites of SARS-CoV-2 Pseudovirus Host Cell Entry
por: Choi, Sheyne S. A., et al.
Publicado: (2022)

Distinct motifs in the E protein are required for SARS-CoV-2 virus particle formation and lysosomal deacidification in host cells
por: Miura, Koya, et al.
Publicado: (2023)

Identification of host dependency factors involved in SARS-CoV-2 replication organelle formation through proteomics and ultrastructural analysis
por: Pahmeier, Felix, et al.
Publicado: (2023)

SARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 Kinase
por: Kettunen, Pinja, et al.
Publicado: (2023)

SARS-CoV-2 NSP12 associates with TRiC and the P323L substitution acts as a host adaption
por: Alruwaili, Muhannad, et al.
Publicado: (2023)

The RNA Helicase eIF4A Is Required for Sapovirus Translation
por: Hosmillo, Myra, et al.
Publicado: (2016)

SARS-CoV-2 Spike Furin Cleavage Site and S2′ Basic Residues Modulate the Entry Process in a Host Cell-Dependent Manner
por: Lavie, Muriel, et al.
Publicado: (2022)

Targeting Doublecortin-Like Kinase 1 (DCLK1)-Regulated SARS-CoV-2 Pathogenesis in COVID-19
por: Undi, Ram Babu, et al.
Publicado: (2022)

A Structurally Conserved RNA Element within SARS-CoV-2 ORF1a RNA and S mRNA Regulates Translation in Response to Viral S Protein-Induced Signaling in Human Lung Cells
por: Basu, Abhijit, et al.
Publicado: (2022)

SARS-CoV-2 NSP12 Protein Is Not an Interferon-β Antagonist
por: Li, Aixin, et al.
Publicado: (2021)

Generation and Characterization of Recombinant SARS-CoV-2 Expressing Reporter Genes
por: Chiem, Kevin, et al.
Publicado: (2021)

SARS-CoV-2 Causes Severe Epithelial Inflammation and Barrier Dysfunction
por: Deinhardt-Emmer, Stefanie, et al.
Publicado: (2021)

The PRRA Insert at the S1/S2 Site Modulates Cellular Tropism of SARS-CoV-2 and ACE2 Usage by the Closely Related Bat RaTG13
por: Liu, Shufeng, et al.
Publicado: (2021)

The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication
por: Nilsson-Payant, Benjamin E., et al.
Publicado: (2021)

Species-Specific Molecular Barriers to SARS-CoV-2 Replication in Bat Cells
por: Aicher, Sophie-Marie, et al.
Publicado: (2022)

Mucosal Gene Expression in Response to SARS-CoV-2 Is Associated with Viral Load
por: Rajagopala, Seesandra V., et al.
Publicado: (2023)

Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition
por: Navaratnarajah, Chanakha K., et al.
Publicado: (2021)

A Versatile Reporter System To Monitor Virus-Infected Cells and Its Application to Dengue Virus and SARS-CoV-2
por: Pahmeier, Felix, et al.
Publicado: (2021)

Direct Activation of Endothelial Cells by SARS-CoV-2 Nucleocapsid Protein Is Blocked by Simvastatin
por: Qian, Yisong, et al.
Publicado: (2021)

The “LLQY” Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles
por: Du, Shouwen, et al.
Publicado: (2022)

Acquisition of Furin Cleavage Site and Further SARS-CoV-2 Evolution Change the Mechanisms of Viral Entry, Infection Spread, and Cell Signaling
por: Frolova, Elena I., et al.
Publicado: (2022)

Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2
por: Zhao, Xuesen, et al.
Publicado: (2020)

Structural Basis for Human Receptor Recognition by SARS-CoV-2 Omicron Variant BA.1
por: Geng, Qibin, et al.
Publicado: (2022)

All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein
por: Frolov, Ilya, et al.
Publicado: (2023)

The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment
por: Harris, Leanne, et al.
Publicado: (2016)

LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2
por: Zhao, Xuesen, et al.
Publicado: (2020)

SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells
por: Nchioua, Rayhane, et al.
Publicado: (2022)

Molecular Basis of Mink ACE2 Binding to SARS-CoV-2 and Its Mink-Derived Variants
por: Su, Chao, et al.
Publicado: (2022)

Detection of Airborne Influenza A and SARS-CoV-2 Virus Shedding following Ocular Inoculation of Ferrets
por: Belser, Jessica A., et al.
Publicado: (2022)

Single-Virus Fusion Measurements Reveal Multiple Mechanistically Equivalent Pathways for SARS-CoV-2 Entry
por: Sengar, Anjali, et al.
Publicado: (2023)

SARS-CoV-2 nsp13 Restricts Episomal DNA Transcription without Affecting Chromosomal DNA
por: Li, Aixin, et al.
Publicado: (2023)

UBR5 Acts as an Antiviral Host Factor against MERS-CoV via Promoting Ubiquitination and Degradation of ORF4b
por: Zhou, Yuzheng, et al.
Publicado: (2022)

Cytoplasmic Tail Truncation Stabilizes S1-S2 Association and Enhances S Protein Incorporation into SARS-CoV-2 Pseudovirions
por: Zhang, Lizhou, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_960dv9kubhegoduorgfa41k8de