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Differential Effect of Deleting Members of African Swine Fever Virus Multigene Families 360 and 505 from the Genotype II Georgia 2007/1 Isolate on Virus Replication, Virulence, and Induction of Protection
African swine fever virus multigene family (MGF) 360 and 505 genes have roles in suppressing the type I interferon response and in virulence in pigs. The role of the individual genes is poorly understood. Different combinations of these genes were deleted from the virulent genotype II Georgia 2007/1...
Autores principales: | Rathakrishnan, Anusyah, Connell, Samuel, Petrovan, Vlad, Moffat, Katy, Goatley, Lynnette C., Jabbar, Tamara, Sánchez-Cordón, Pedro J., Reis, Ana L., Dixon, Linda K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941908/ https://www.ncbi.nlm.nih.gov/pubmed/35044212 http://dx.doi.org/10.1128/jvi.01899-21 |
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