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Birnaviridae Virus Factories Show Features of Liquid-Liquid Phase Separation and Are Distinct from Paracrystalline Arrays of Virions Observed by Electron Microscopy

To gain more information about the nature of Birnaviridae virus factories (VFs), we used a recombinant infectious bursal disease virus (IBDV) expressing split-GFP11 tagged to the polymerase (VP1) that we have previously shown is a marker for VFs in infected cells expressing GFP1-10. We found that VF...

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Detalles Bibliográficos
Autores principales: Reddy, Vishwanatha R. A. P., Campbell, Elle A., Wells, Joanna, Simpson, Jennifer, Nazki, Salik, Hawes, Philippa C., Broadbent, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941928/
https://www.ncbi.nlm.nih.gov/pubmed/35138130
http://dx.doi.org/10.1128/jvi.02024-21