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Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection

Olfactory and gustatory disorders are prominent symptoms of acute COVID-19. Although both senses recover in many patients within weeks to months, persistency has been described in up to 60%. However up to now most reports on the course of chemosensitive disorders after COVID-19 are not based on psyc...

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Autores principales: Hintschich, Constantin A., Fischer, René, Hummel, Thomas, Wenzel, Jürgen J., Bohr, Christopher, Vielsmeier, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942205/
https://www.ncbi.nlm.nih.gov/pubmed/35320821
http://dx.doi.org/10.1371/journal.pone.0265686
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author Hintschich, Constantin A.
Fischer, René
Hummel, Thomas
Wenzel, Jürgen J.
Bohr, Christopher
Vielsmeier, Veronika
author_facet Hintschich, Constantin A.
Fischer, René
Hummel, Thomas
Wenzel, Jürgen J.
Bohr, Christopher
Vielsmeier, Veronika
author_sort Hintschich, Constantin A.
collection PubMed
description Olfactory and gustatory disorders are prominent symptoms of acute COVID-19. Although both senses recover in many patients within weeks to months, persistency has been described in up to 60%. However up to now most reports on the course of chemosensitive disorders after COVID-19 are not based on psychophysical testing but only on subjective patients’ ratings. In this study we assessed both olfaction and gustation using psychophysical tests eight months after COVID-19. Validated psychophysical testing revealed hyposmia in 18% and hypogeusia in even 32% of 303 included patients. This shows that olfactory and especially gustatory disorders have to be seen as important chronic symptoms post-COVID-19. The high prevalence of gustatory dysfunction indicates that gustatory function does not recover or might even deteriorate in the months following the acute infection.
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spelling pubmed-89422052022-03-24 Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection Hintschich, Constantin A. Fischer, René Hummel, Thomas Wenzel, Jürgen J. Bohr, Christopher Vielsmeier, Veronika PLoS One Research Article Olfactory and gustatory disorders are prominent symptoms of acute COVID-19. Although both senses recover in many patients within weeks to months, persistency has been described in up to 60%. However up to now most reports on the course of chemosensitive disorders after COVID-19 are not based on psychophysical testing but only on subjective patients’ ratings. In this study we assessed both olfaction and gustation using psychophysical tests eight months after COVID-19. Validated psychophysical testing revealed hyposmia in 18% and hypogeusia in even 32% of 303 included patients. This shows that olfactory and especially gustatory disorders have to be seen as important chronic symptoms post-COVID-19. The high prevalence of gustatory dysfunction indicates that gustatory function does not recover or might even deteriorate in the months following the acute infection. Public Library of Science 2022-03-23 /pmc/articles/PMC8942205/ /pubmed/35320821 http://dx.doi.org/10.1371/journal.pone.0265686 Text en © 2022 Hintschich et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Hintschich, Constantin A.
Fischer, René
Hummel, Thomas
Wenzel, Jürgen J.
Bohr, Christopher
Vielsmeier, Veronika
Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection
title Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection
title_full Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection
title_fullStr Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection
title_full_unstemmed Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection
title_short Persisting olfactory dysfunction in post-COVID-19 is associated with gustatory impairment: Results from chemosensitive testing eight months after the acute infection
title_sort persisting olfactory dysfunction in post-covid-19 is associated with gustatory impairment: results from chemosensitive testing eight months after the acute infection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942205/
https://www.ncbi.nlm.nih.gov/pubmed/35320821
http://dx.doi.org/10.1371/journal.pone.0265686
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