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Characterization of intrinsically disordered regions in proteins informed by human genetic diversity
All proteomes contain both proteins and polypeptide segments that don’t form a defined three-dimensional structure yet are biologically active—called intrinsically disordered proteins and regions (IDPs and IDRs). Most of these IDPs/IDRs lack useful functional annotation limiting our understanding of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942211/ https://www.ncbi.nlm.nih.gov/pubmed/35275927 http://dx.doi.org/10.1371/journal.pcbi.1009911 |