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Double-antigen sandwich ELISA based on chimeric antigens for detection of antibodies to Trypanosoma cruzi in human sera
BACKGROUND: Enzyme-linked immunosorbent assays (ELISA) are generally the chosen test for Chagas disease (CD) diagnosis; however, its performance depends on the antigen preparation adsorbed to the solid phase, which may lead to false-positive results and cross-reactions. The use of chimeric recombina...
Autores principales: | Freitas, Natália Erdens Maron, Santos, Emily Ferreira, Leony, Leonardo Maia, Silva, Ângelo Antônio Oliveira, Daltro, Ramona Tavares, Vasconcelos, Larissa de Carvalho Medrado, Duarte, Gabriela Agra, Oliveira da Mota, Cristiane, Silva, Edimilson Domingos, Celedon, Paola Alejandra Fiorani, Zanchin, Nilson Ivo Tonin, Santos, Fred Luciano Neves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942226/ https://www.ncbi.nlm.nih.gov/pubmed/35275913 http://dx.doi.org/10.1371/journal.pntd.0010290 |
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