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Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8

Radiotherapy is a mainstay cancer therapy whose antitumor effects partially depend on T cell responses. However, the role of Natural Killer (NK) cells in radiotherapy remains unclear. Here, using a reverse translational approach, we show a central role of NK cells in the radiation-induced immune res...

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Detalles Bibliográficos
Autores principales: Walle, Thomas, Kraske, Joscha A., Liao, Boyu, Lenoir, Bénédicte, Timke, Carmen, von Bohlen und Halbach, Emilia, Tran, Florian, Griebel, Paul, Albrecht, Dorothee, Ahmed, Azaz, Suarez-Carmona, Meggy, Jiménez-Sánchez, Alejandro, Beikert, Tizian, Tietz-Dahlfuß, Alexandra, Menevse, Ayse Nur, Schmidt, Gabriele, Brom, Manuela, Pahl, Jens H. W., Antonopoulos, Wiebke, Miller, Matthias, Perez, Ramon Lopez, Bestvater, Felix, Giese, Nathalia A., Beckhove, Philipp, Rosenstiel, Philip, Jäger, Dirk, Strobel, Oliver, Pe’er, Dana, Halama, Niels, Debus, Jürgen, Cerwenka, Adelheid, Huber, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942354/
https://www.ncbi.nlm.nih.gov/pubmed/35319989
http://dx.doi.org/10.1126/sciadv.abh4050