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Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions

Cells probe their microenvironment using membrane protrusion-retraction cycles. Spatiotemporal coordination of Rac1 and RhoA GTP-binding activities initiates and reinforces protrusions and retractions, but the control of their finite lifetime remains unclear. We examined the relations of Rac1 and Rh...

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Detalles Bibliográficos
Autores principales:	Hu, Jianjiang, Gong, Xiaowei, Strömblad, Staffan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942371/ https://www.ncbi.nlm.nih.gov/pubmed/35319996 http://dx.doi.org/10.1126/sciadv.abl3667

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