Temporal control of the integrated stress response by a stochastic molecular switch

Stress granules (SGs) are formed in the cytosol as an acute response to environmental cues and activation of the integrated stress response (ISR), a central signaling pathway controlling protein synthesis. Using chronic virus infection as stress model, we previously uncovered a unique temporal contr...

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Detalles Bibliográficos
Autores principales: Klein, Philipp, Kallenberger, Stefan M., Roth, Hanna, Roth, Karsten, Ly-Hartig, Thi Bach Nga, Magg, Vera, Aleš, Janez, Talemi, Soheil Rastgou, Qiang, Yu, Wolf, Steffen, Oleksiuk, Olga, Kurilov, Roma, Di Ventura, Barbara, Bartenschlager, Ralf, Eils, Roland, Rohr, Karl, Hamprecht, Fred A., Höfer, Thomas, Fackler, Oliver T., Stoecklin, Georg, Ruggieri, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942376/
https://www.ncbi.nlm.nih.gov/pubmed/35319985
http://dx.doi.org/10.1126/sciadv.abk2022

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