AP-1 signaling pathway promotes pro-IL-1β transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection

NLRP3 inflammasome mainly controls interleukin-1β (IL-1β) secretion, leading to cell death called pyroptosis constituting a major antiviral host defense and inflammatory diseases upon viral infection. The RAF-MEK1/2-ERK1/2 cascade and downstream c-Jun/Fos and Activator protein-1 (AP1) signaling path...

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Detalles Bibliográficos
Autores principales: Wan, Pin, Zhang, Simeng, Ruan, Zhihui, Liu, Xueli, Yang, Ge, Jia, Yaling, Li, Yongkui, Pan, Pan, Wang, Wenbiao, Li, Geng, Chen, Xulin, Liu, Zhixin, Zhang, Qiwei, Luo, Zhen, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942419/
https://www.ncbi.nlm.nih.gov/pubmed/35300578
http://dx.doi.org/10.1080/21505594.2022.2040188

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