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Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth

The Ewing sarcoma family of tumors is a group of malignant small round blue cell tumors (SRBCTs) that affect children, adolescents, and young adults. The tumors are characterized by reciprocal chromosomal translocations that generate chimeric fusion oncogenes, the most common of which is EWSR1-FLI1....

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Detalles Bibliográficos
Autores principales: Vasileva, Elena, Warren, Mikako, Triche, Timothy J, Amatruda, James F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942468/
https://www.ncbi.nlm.nih.gov/pubmed/35285802
http://dx.doi.org/10.7554/eLife.69734