Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

As regioisomers/bioisosteres of 1a, a 4-phenylbenzamide tranylcypromine (TCP) derivative previously disclosed by us, we report here the synthesis and biological evaluation of some (hetero)arylbenzoylamino TCP derivatives 1b-6, in which the 4-phenyl moiety of 1a was shifted at the benzamide C3 positi...

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Detalles Bibliográficos
Autores principales: Fioravanti, Rossella, Rodriguez, Veronica, Caroli, Jonatan, Chianese, Ugo, Benedetti, Rosaria, Di Bello, Elisabetta, Noce, Beatrice, Zwergel, Clemens, Corinti, Davide, Viña, Dolores, Altucci, Lucia, Mattevi, Andrea, Valente, Sergio, Mai, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942502/
https://www.ncbi.nlm.nih.gov/pubmed/35317680
http://dx.doi.org/10.1080/14756366.2022.2052869

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