Cargando…

Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway

Renal fibrosis is a common characteristic and the final pathological mechanism of chronic kidney disease (CKD). Although CKD remains incurable, inhibition of renal fibrosis is beneficial to inhibit the CKD process. Relaxin alleviates renal fibrosis in some experimental models, but its mechanism rema...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feiteng, Chen, Lei, Chen, Deng, Li, Chaoliang, Xu, Zijie, Xu, Yi, Shao, Minglei, Sha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Laboratory Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942541/ https://www.ncbi.nlm.nih.gov/pubmed/35311469 http://dx.doi.org/10.1080/0886022X.2022.2044351

Ejemplares similares

The influence of fasudil on renal proximal tubular cell epithelial–mesenchymal transition induced by parathormone
por: Gao, Ziqing, et al.
Publicado: (2017)

Effect of 5/6 Nephrectomized Rat Serum on Epithelial-to-Mesenchymal Transition In Vitro
por: Lu, Zhaoyu, et al.
Publicado: (2011)

A comprehensive analysis of Wnt/β-catenin signaling pathway-related genes and crosstalk pathways in the treatment of As(2)O(3) in renal cancer
por: Li, Yan-Lei, et al.
Publicado: (2018)

MiR-122-5p promotes peritoneal fibrosis in a rat model of peritoneal dialysis by targeting Smad5 to activate Wnt/β-catenin pathway
por: Liu, Yirong, et al.
Publicado: (2022)

Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway
por: Zhou, X, et al.
Publicado: (2015)

Puerarin attenuates renal fibrosis by reducing oxidative stress induced-epithelial cell apoptosis via MAPK signal pathways in vivo and in vitro
por: Zhou, Xiangjun, et al.
Publicado: (2017)

Intermedin protects HUVECs from ischemia reperfusion injury via Wnt/β-catenin signaling pathway
por: Wang, Yanhong, et al.
Publicado: (2019)

DACH1, a novel target of miR-218, participates in the regulation of cell viability, apoptosis, inflammatory response, and epithelial-mesenchymal transition process in renal tubule cells treated by high-glucose
por: Zhang, Ying-Li, et al.
Publicado: (2020)

Tamibarotene inhibit the accumulation of fibrocyte and alleviate renal fibrosis by IL-17A
por: Li, Lixi, et al.
Publicado: (2020)

The antioxidative effects of empagliflozin on high glucose‑induced epithelial-mesenchymal transition in peritoneal mesothelial cells via the Nrf2/HO-1 signaling
por: Shi, Ping, et al.
Publicado: (2022)

Baicalein protects renal tubular epithelial cells againsthypoxia-reoxygenation injury
por: Chen, Chun, et al.
Publicado: (2018)

Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway [Corrigendum]
Publicado: (2017)

APMAP Promotes Epithelial-Mesenchymal Transition and Metastasis of Cervical Cancer Cells by Activating the Wnt/β-catenin Pathway
por: Zhu, Xiuting, et al.
Publicado: (2021)

3,3′-Diindolylmethane ameliorates renal fibrosis through the inhibition of renal fibroblast activation in vivo and in vitro
por: Xia, Zun-En, et al.
Publicado: (2018)

Protective effect of bone marrow mesenchymal stem cells modified with klotho on renal ischemia-reperfusion injury
por: Xie, Li-Bo, et al.
Publicado: (2019)

Identification of circular RNA expression profiles in renal fibrosis induced by obstructive injury
por: Huang, Jiangju, et al.
Publicado: (2021)

Curcumin mediates repulsive guidance molecule B (RGMb) in the treatment mechanism of renal fibrosis induced by unilateral ureteral obstruction
por: Chen, Fei, et al.
Publicado: (2021)

Interleukin-23 promotes the epithelial-mesenchymal transition of oesophageal carcinoma cells via the Wnt/β-catenin pathway
por: Chen, Deyu, et al.
Publicado: (2015)

Silibinin inhibits epithelial-mesenchymal transition of renal cell carcinoma through autophagy-dependent Wnt/β-catenin signaling
por: Fan, Yizeng, et al.
Publicado: (2020)

Arctigenin Suppressed Epithelial-Mesenchymal Transition Through Wnt3a/β-Catenin Pathway in PQ-Induced Pulmonary Fibrosis
por: Gao, Fei, et al.
Publicado: (2020)

Cadherin 13 Inhibits Pancreatic Cancer Progression and Epithelial-mesenchymal Transition by Wnt/β-Catenin Signaling
por: Xu, Dengfei, et al.
Publicado: (2020)

Optimal Ratio of Wnt3a Expression in Human Mesenchymal Stem Cells Promotes Axonal Regeneration in Spinal Cord Injured Rat Model
por: Yoon, Hyung Ho, et al.
Publicado: (2021)

Renal tubular epithelial cells injury induced by mannitol and its potential mechanism
por: Shi, Jinwan, et al.
Publicado: (2018)

Salinomycin repressed the epithelial–mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-catenin pathway
por: Li, Rui, et al.
Publicado: (2017)

MicroRNAs target the Wnt/β-catenin signaling pathway to regulate epithelial-mesenchymal transition in cancer
por: Lei, Yuhe, et al.
Publicado: (2020)

Ferroptosis‐related gene CHAC1 is a valid indicator for the poor prognosis of kidney renal clear cell carcinoma
por: Li, Deng, et al.
Publicado: (2021)

CD147 promotes epithelial-mesenchymal transition of prostate cancer cells via the Wnt/β-catenin pathway
por: Fang, Fang, et al.
Publicado: (2020)

Relaxin abrogates renal interstitial fibrosis by regulating macrophage polarization via inhibition of Toll-like receptor 4 signaling
por: Chen, Lei, et al.
Publicado: (2017)

Renoprotective effects of a dipeptidyl peptidase 4 inhibitor in a mouse model of progressive renal fibrosis
por: Uchida, Takahiro, et al.
Publicado: (2017)

Combination therapy with DHA and BMSCs suppressed podocyte injury and attenuated renal fibrosis by modulating the TGF-β1/Smad pathway in MN mice
por: Li, Yongzhang, et al.
Publicado: (2023)

A Positive Role of Cadherin in Wnt/β-Catenin Signalling during Epithelial-Mesenchymal Transition
por: Howard, Sara, et al.
Publicado: (2011)

Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signaling
por: Bernaudo, S, et al.
Publicado: (2016)

Fascin Induces Epithelial-Mesenchymal Transition of Cholangiocarcinoma Cells by Regulating Wnt/β-Catenin Signaling
por: Mao, Xianhai, et al.
Publicado: (2016)

ING5 inhibits lung cancer invasion and epithelial–mesenchymal transition by inhibiting the WNT/β‐catenin pathway
por: Liu, Xin‐Li, et al.
Publicado: (2019)

H(2)S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression
por: Li, Yan, et al.
Publicado: (2016)

FERMT3 mediates cigarette smoke-induced epithelial–mesenchymal transition through Wnt/β-catenin signaling
por: Su, Xiaoshan, et al.
Publicado: (2021)

CCR9 initiates epithelial–mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis
por: Kong, Haoran, et al.
Publicado: (2021)

Deletion of discoidin domain receptor 2 attenuates renal interstitial fibrosis in a murine unilateral ureteral obstruction model
por: Li, Xi’an, et al.
Publicado: (2019)

An optimized 5/6 nephrectomy mouse model based on unilateral kidney ligation and its application in renal fibrosis research
por: Tan, Rui-Zhi, et al.
Publicado: (2019)

Silencing of RIPK4 inhibits epithelial-mesenchymal transition by inactivating the Wnt/β-catenin signaling pathway in osteosarcoma
por: Yi, Zhigang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_upjil8e3au19la5lj72qadrq0f