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Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors

In order to investigate the efficacy of mosapril citrate combined with ShenQu Xiaoshi oral liquid in the treatment of children with functional dyspepsia and the effect on serum cytokines, 136 children with functional dyspepsia admitted from May 2017 to September 2020 were divided into 2 groups rando...

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Autores principales: Dou, Zhenyun, Xu, Zhou, Wang, Qizheng, Li, Jiangshu, Yu, Chunlin, Miao, Yequan, Ren, Tailiang, Wang, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942657/
https://www.ncbi.nlm.nih.gov/pubmed/35340223
http://dx.doi.org/10.1155/2022/3053277
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author Dou, Zhenyun
Xu, Zhou
Wang, Qizheng
Li, Jiangshu
Yu, Chunlin
Miao, Yequan
Ren, Tailiang
Wang, Haijun
author_facet Dou, Zhenyun
Xu, Zhou
Wang, Qizheng
Li, Jiangshu
Yu, Chunlin
Miao, Yequan
Ren, Tailiang
Wang, Haijun
author_sort Dou, Zhenyun
collection PubMed
description In order to investigate the efficacy of mosapril citrate combined with ShenQu Xiaoshi oral liquid in the treatment of children with functional dyspepsia and the effect on serum cytokines, 136 children with functional dyspepsia admitted from May 2017 to September 2020 were divided into 2 groups randomly, 68 cases in each group. The western medicine group was treated with mosapril citrate tablets, and the combined group was treated with Shenqu xiaoshi oral liquid on the basis of the western medicine group. The efficacy of patients was evaluated 14 days after treatment, and the safety, symptom score, and serum cytokines of the two groups were compared. The results showed that, after 14 days of treatment, the scores of abdominal distension and abdominal pain (ADAP), lack of food (LOF), nausea and vomiting (NAV), irregular stool (IS), and mental fatigue (MF) in the combined group were all lower than those in the western group (P < 0.05). There was no statistical significance in the incidence of diarrhea, abnormal liver and kidney, and allergic rash between the two groups (p > 0.05). In conclusion, mosapride citrate tablets combined with Shenqu Xiaoshi oral liquid can achieve good therapeutic effects in children with functional dyspepsia, reduce symptom scores, improve serum cytokine levels, and have high drug safety, which is worthy of promotion and application.
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spelling pubmed-89426572022-03-24 Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors Dou, Zhenyun Xu, Zhou Wang, Qizheng Li, Jiangshu Yu, Chunlin Miao, Yequan Ren, Tailiang Wang, Haijun J Healthc Eng Research Article In order to investigate the efficacy of mosapril citrate combined with ShenQu Xiaoshi oral liquid in the treatment of children with functional dyspepsia and the effect on serum cytokines, 136 children with functional dyspepsia admitted from May 2017 to September 2020 were divided into 2 groups randomly, 68 cases in each group. The western medicine group was treated with mosapril citrate tablets, and the combined group was treated with Shenqu xiaoshi oral liquid on the basis of the western medicine group. The efficacy of patients was evaluated 14 days after treatment, and the safety, symptom score, and serum cytokines of the two groups were compared. The results showed that, after 14 days of treatment, the scores of abdominal distension and abdominal pain (ADAP), lack of food (LOF), nausea and vomiting (NAV), irregular stool (IS), and mental fatigue (MF) in the combined group were all lower than those in the western group (P < 0.05). There was no statistical significance in the incidence of diarrhea, abnormal liver and kidney, and allergic rash between the two groups (p > 0.05). In conclusion, mosapride citrate tablets combined with Shenqu Xiaoshi oral liquid can achieve good therapeutic effects in children with functional dyspepsia, reduce symptom scores, improve serum cytokine levels, and have high drug safety, which is worthy of promotion and application. Hindawi 2022-03-16 /pmc/articles/PMC8942657/ /pubmed/35340223 http://dx.doi.org/10.1155/2022/3053277 Text en Copyright © 2022 Zhenyun Dou et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Dou, Zhenyun
Xu, Zhou
Wang, Qizheng
Li, Jiangshu
Yu, Chunlin
Miao, Yequan
Ren, Tailiang
Wang, Haijun
Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors
title Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors
title_full Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors
title_fullStr Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors
title_full_unstemmed Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors
title_short Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors
title_sort mosapride citrate combined with divine qu disinfectant oral liquid for children function dyspepsia and the influence of serum factors
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942657/
https://www.ncbi.nlm.nih.gov/pubmed/35340223
http://dx.doi.org/10.1155/2022/3053277
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