Cargando…
Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors
In order to investigate the efficacy of mosapril citrate combined with ShenQu Xiaoshi oral liquid in the treatment of children with functional dyspepsia and the effect on serum cytokines, 136 children with functional dyspepsia admitted from May 2017 to September 2020 were divided into 2 groups rando...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942657/ https://www.ncbi.nlm.nih.gov/pubmed/35340223 http://dx.doi.org/10.1155/2022/3053277 |
_version_ | 1784673349979340800 |
---|---|
author | Dou, Zhenyun Xu, Zhou Wang, Qizheng Li, Jiangshu Yu, Chunlin Miao, Yequan Ren, Tailiang Wang, Haijun |
author_facet | Dou, Zhenyun Xu, Zhou Wang, Qizheng Li, Jiangshu Yu, Chunlin Miao, Yequan Ren, Tailiang Wang, Haijun |
author_sort | Dou, Zhenyun |
collection | PubMed |
description | In order to investigate the efficacy of mosapril citrate combined with ShenQu Xiaoshi oral liquid in the treatment of children with functional dyspepsia and the effect on serum cytokines, 136 children with functional dyspepsia admitted from May 2017 to September 2020 were divided into 2 groups randomly, 68 cases in each group. The western medicine group was treated with mosapril citrate tablets, and the combined group was treated with Shenqu xiaoshi oral liquid on the basis of the western medicine group. The efficacy of patients was evaluated 14 days after treatment, and the safety, symptom score, and serum cytokines of the two groups were compared. The results showed that, after 14 days of treatment, the scores of abdominal distension and abdominal pain (ADAP), lack of food (LOF), nausea and vomiting (NAV), irregular stool (IS), and mental fatigue (MF) in the combined group were all lower than those in the western group (P < 0.05). There was no statistical significance in the incidence of diarrhea, abnormal liver and kidney, and allergic rash between the two groups (p > 0.05). In conclusion, mosapride citrate tablets combined with Shenqu Xiaoshi oral liquid can achieve good therapeutic effects in children with functional dyspepsia, reduce symptom scores, improve serum cytokine levels, and have high drug safety, which is worthy of promotion and application. |
format | Online Article Text |
id | pubmed-8942657 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-89426572022-03-24 Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors Dou, Zhenyun Xu, Zhou Wang, Qizheng Li, Jiangshu Yu, Chunlin Miao, Yequan Ren, Tailiang Wang, Haijun J Healthc Eng Research Article In order to investigate the efficacy of mosapril citrate combined with ShenQu Xiaoshi oral liquid in the treatment of children with functional dyspepsia and the effect on serum cytokines, 136 children with functional dyspepsia admitted from May 2017 to September 2020 were divided into 2 groups randomly, 68 cases in each group. The western medicine group was treated with mosapril citrate tablets, and the combined group was treated with Shenqu xiaoshi oral liquid on the basis of the western medicine group. The efficacy of patients was evaluated 14 days after treatment, and the safety, symptom score, and serum cytokines of the two groups were compared. The results showed that, after 14 days of treatment, the scores of abdominal distension and abdominal pain (ADAP), lack of food (LOF), nausea and vomiting (NAV), irregular stool (IS), and mental fatigue (MF) in the combined group were all lower than those in the western group (P < 0.05). There was no statistical significance in the incidence of diarrhea, abnormal liver and kidney, and allergic rash between the two groups (p > 0.05). In conclusion, mosapride citrate tablets combined with Shenqu Xiaoshi oral liquid can achieve good therapeutic effects in children with functional dyspepsia, reduce symptom scores, improve serum cytokine levels, and have high drug safety, which is worthy of promotion and application. Hindawi 2022-03-16 /pmc/articles/PMC8942657/ /pubmed/35340223 http://dx.doi.org/10.1155/2022/3053277 Text en Copyright © 2022 Zhenyun Dou et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Dou, Zhenyun Xu, Zhou Wang, Qizheng Li, Jiangshu Yu, Chunlin Miao, Yequan Ren, Tailiang Wang, Haijun Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors |
title | Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors |
title_full | Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors |
title_fullStr | Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors |
title_full_unstemmed | Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors |
title_short | Mosapride Citrate Combined with Divine Qu Disinfectant Oral Liquid for Children Function Dyspepsia and the Influence of Serum Factors |
title_sort | mosapride citrate combined with divine qu disinfectant oral liquid for children function dyspepsia and the influence of serum factors |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942657/ https://www.ncbi.nlm.nih.gov/pubmed/35340223 http://dx.doi.org/10.1155/2022/3053277 |
work_keys_str_mv | AT douzhenyun mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors AT xuzhou mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors AT wangqizheng mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors AT lijiangshu mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors AT yuchunlin mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors AT miaoyequan mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors AT rentailiang mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors AT wanghaijun mosapridecitratecombinedwithdivinequdisinfectantoralliquidforchildrenfunctiondyspepsiaandtheinfluenceofserumfactors |