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The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study

BACKGROUND: COVID-19 vaccinations are intended to help produce neutralizing antibodies which target surface spike protein to combat the SARS-Cov-2 virus. Similarly, COVID-19 recovered patients exhibit high levels of SARS-CoV-2 neutralizing antibodies, which predominantly target the surface spike pro...

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Detalles Bibliográficos
Autores principales: Shrestha, Yogendra, Venkataraman, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942717/
https://www.ncbi.nlm.nih.gov/pubmed/35345826
http://dx.doi.org/10.1016/j.vacun.2022.03.002
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author Shrestha, Yogendra
Venkataraman, Rajesh
author_facet Shrestha, Yogendra
Venkataraman, Rajesh
author_sort Shrestha, Yogendra
collection PubMed
description BACKGROUND: COVID-19 vaccinations are intended to help produce neutralizing antibodies which target surface spike protein to combat the SARS-Cov-2 virus. Similarly, COVID-19 recovered patients exhibit high levels of SARS-CoV-2 neutralizing antibodies, which predominantly target the surface spike protein and are associated with the occurrence of health consequences in survivors. OBJECTIVE: The aim of the study is to explore the long-term health consequences of the COVID-19 vaccines. METHODOLOGY: A prospective, exploratory observational study conducted both online and offline using various questionnaires with all immunized individuals who had been inoculated for at least a month following their last COVID-19 vaccine either AZD1222® or BBV152® vaccines. RESULTS: We evaluated 258 individuals who had taken the COVID vaccine and found that females made up the majority (54.3%) and that the mean age was 24 years. Post-vaccination long-term health issues were reported by 36.05% (93) of the participants, with 37.86% (53) of females and 33.9% (40) of males (p = 0.292). Myalgia was reported by 20.15% (52), fatigue was 13.95% (36), paresthesia was 1.16% (3), ageusia was 0.77% (2), sadness/irritability was 2.31% (6), and lack of concentration/excessive worry was 3.1% (8). CONCLUSIONS: Myalgia, fatigue, paresthesia, ageusia, coughs and colds, dyspnea, sadness/irritability, and lack of concentration/excessive worry are health consequences related to the COVID-19 vaccination which follow a similar pattern of post-COVID syndrome.
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spelling pubmed-89427172022-03-24 The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study Shrestha, Yogendra Venkataraman, Rajesh Vacunas Original BACKGROUND: COVID-19 vaccinations are intended to help produce neutralizing antibodies which target surface spike protein to combat the SARS-Cov-2 virus. Similarly, COVID-19 recovered patients exhibit high levels of SARS-CoV-2 neutralizing antibodies, which predominantly target the surface spike protein and are associated with the occurrence of health consequences in survivors. OBJECTIVE: The aim of the study is to explore the long-term health consequences of the COVID-19 vaccines. METHODOLOGY: A prospective, exploratory observational study conducted both online and offline using various questionnaires with all immunized individuals who had been inoculated for at least a month following their last COVID-19 vaccine either AZD1222® or BBV152® vaccines. RESULTS: We evaluated 258 individuals who had taken the COVID vaccine and found that females made up the majority (54.3%) and that the mean age was 24 years. Post-vaccination long-term health issues were reported by 36.05% (93) of the participants, with 37.86% (53) of females and 33.9% (40) of males (p = 0.292). Myalgia was reported by 20.15% (52), fatigue was 13.95% (36), paresthesia was 1.16% (3), ageusia was 0.77% (2), sadness/irritability was 2.31% (6), and lack of concentration/excessive worry was 3.1% (8). CONCLUSIONS: Myalgia, fatigue, paresthesia, ageusia, coughs and colds, dyspnea, sadness/irritability, and lack of concentration/excessive worry are health consequences related to the COVID-19 vaccination which follow a similar pattern of post-COVID syndrome. Elsevier España, S.L.U. 2022 2022-03-24 /pmc/articles/PMC8942717/ /pubmed/35345826 http://dx.doi.org/10.1016/j.vacun.2022.03.002 Text en © 2022 Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original
Shrestha, Yogendra
Venkataraman, Rajesh
The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study
title The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study
title_full The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study
title_fullStr The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study
title_full_unstemmed The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study
title_short The prevalence of inverse health consequences of COVID-19 vaccines: A post-vaccination study
title_sort prevalence of inverse health consequences of covid-19 vaccines: a post-vaccination study
topic Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942717/
https://www.ncbi.nlm.nih.gov/pubmed/35345826
http://dx.doi.org/10.1016/j.vacun.2022.03.002
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