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Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages

PURPOSE: There are over 1.3 million colorectal cancer (CRC) survivors in the USA, many of whom report lower health-related quality of life (HRQoL) years after treatment. This study aimed to explore the effect of digital health tools on HRQoL in CRC survivors. METHODS: We conducted a two-arm, randomi...

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Autores principales: Chan, Hilary, Van Loon, Katherine, Kenfield, Stacey A., Chan, June M., Mitchell, Emily, Zhang, Li, Paciorek, Alan, Joseph, Galen, Laffan, Angela, Atreya, Chloe, Fukuoka, Yoshimi, Miaskowski, Christine, Meyerhardt, Jeffrey A., Venook, Alan P., Van Blarigan, Erin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942969/
https://www.ncbi.nlm.nih.gov/pubmed/35119520
http://dx.doi.org/10.1007/s00520-022-06870-5
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author Chan, Hilary
Van Loon, Katherine
Kenfield, Stacey A.
Chan, June M.
Mitchell, Emily
Zhang, Li
Paciorek, Alan
Joseph, Galen
Laffan, Angela
Atreya, Chloe
Fukuoka, Yoshimi
Miaskowski, Christine
Meyerhardt, Jeffrey A.
Venook, Alan P.
Van Blarigan, Erin L.
author_facet Chan, Hilary
Van Loon, Katherine
Kenfield, Stacey A.
Chan, June M.
Mitchell, Emily
Zhang, Li
Paciorek, Alan
Joseph, Galen
Laffan, Angela
Atreya, Chloe
Fukuoka, Yoshimi
Miaskowski, Christine
Meyerhardt, Jeffrey A.
Venook, Alan P.
Van Blarigan, Erin L.
author_sort Chan, Hilary
collection PubMed
description PURPOSE: There are over 1.3 million colorectal cancer (CRC) survivors in the USA, many of whom report lower health-related quality of life (HRQoL) years after treatment. This study aimed to explore the effect of digital health tools on HRQoL in CRC survivors. METHODS: We conducted a two-arm, randomized controlled trial of 42 subjects who had completed treatment for CRC. Participants in the intervention arm received a Fitbit Flex™ and daily text messages for 12 weeks. HRQoL was assessed as a secondary endpoint in both arms at enrollment and 12 weeks using the Medical Outcomes Study Short Form Survey (SF-36) and the Functional Assessment of Cancer Therapy–Colorectal (FACT-C). Survey score changes from enrollment to 12 weeks were compared between the two arms using independent t tests, and scores at enrollment and 12 weeks were compared using paired t tests. RESULTS: An increase in the FACT-C functional well-being subscale was observed in individuals in the intervention arm pre- to post-intervention (median difference, 2; interquartile range (IQR), 1, 4; P = .02). Although the between-group comparison was not statistically significant, no change in the functional well-being subscale was observed in the control arm (median difference, 0; IQR, 1, 1; P = .71). No other measures of HRQoL appeared to differ within arm across time points or between arms. CONCLUSION: A 12-week digital physical activity intervention may improve functional well-being among CRC survivors. Larger randomized studies are needed to determine if digital health tools improve functional well-being among CRC survivors and if this improvement can be sustained over time. TRIAL REGISTRATION: NCT02966054; registration date, November 17, 2016 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00520-022-06870-5.
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spelling pubmed-89429692022-04-07 Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages Chan, Hilary Van Loon, Katherine Kenfield, Stacey A. Chan, June M. Mitchell, Emily Zhang, Li Paciorek, Alan Joseph, Galen Laffan, Angela Atreya, Chloe Fukuoka, Yoshimi Miaskowski, Christine Meyerhardt, Jeffrey A. Venook, Alan P. Van Blarigan, Erin L. Support Care Cancer Original Article PURPOSE: There are over 1.3 million colorectal cancer (CRC) survivors in the USA, many of whom report lower health-related quality of life (HRQoL) years after treatment. This study aimed to explore the effect of digital health tools on HRQoL in CRC survivors. METHODS: We conducted a two-arm, randomized controlled trial of 42 subjects who had completed treatment for CRC. Participants in the intervention arm received a Fitbit Flex™ and daily text messages for 12 weeks. HRQoL was assessed as a secondary endpoint in both arms at enrollment and 12 weeks using the Medical Outcomes Study Short Form Survey (SF-36) and the Functional Assessment of Cancer Therapy–Colorectal (FACT-C). Survey score changes from enrollment to 12 weeks were compared between the two arms using independent t tests, and scores at enrollment and 12 weeks were compared using paired t tests. RESULTS: An increase in the FACT-C functional well-being subscale was observed in individuals in the intervention arm pre- to post-intervention (median difference, 2; interquartile range (IQR), 1, 4; P = .02). Although the between-group comparison was not statistically significant, no change in the functional well-being subscale was observed in the control arm (median difference, 0; IQR, 1, 1; P = .71). No other measures of HRQoL appeared to differ within arm across time points or between arms. CONCLUSION: A 12-week digital physical activity intervention may improve functional well-being among CRC survivors. Larger randomized studies are needed to determine if digital health tools improve functional well-being among CRC survivors and if this improvement can be sustained over time. TRIAL REGISTRATION: NCT02966054; registration date, November 17, 2016 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00520-022-06870-5. Springer Berlin Heidelberg 2022-02-04 2022 /pmc/articles/PMC8942969/ /pubmed/35119520 http://dx.doi.org/10.1007/s00520-022-06870-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Chan, Hilary
Van Loon, Katherine
Kenfield, Stacey A.
Chan, June M.
Mitchell, Emily
Zhang, Li
Paciorek, Alan
Joseph, Galen
Laffan, Angela
Atreya, Chloe
Fukuoka, Yoshimi
Miaskowski, Christine
Meyerhardt, Jeffrey A.
Venook, Alan P.
Van Blarigan, Erin L.
Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages
title Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages
title_full Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages
title_fullStr Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages
title_full_unstemmed Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages
title_short Quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages
title_sort quality of life of colorectal cancer survivors participating in a pilot randomized controlled trial of physical activity trackers and daily text messages
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942969/
https://www.ncbi.nlm.nih.gov/pubmed/35119520
http://dx.doi.org/10.1007/s00520-022-06870-5
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