Impact of yellow fever virus envelope protein on wild-type and vaccine epitopes and tissue tropism

The envelope (E) protein of flaviviruses is functionally associated with viral tissue tropism and pathogenicity. For yellow fever virus (YFV), viscerotropic disease primarily involving the liver is pathognomonic for wild-type (WT) infection. In contrast, the live-attenuated vaccine (LAV) strain 17D...

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Detalles Bibliográficos
Autores principales: Davis, Emily H., Wang, Binbin, White, Mellodee, Huang, Yan-Jang S., Sarathy, Vanessa V., Wang, Tian, Bourne, Nigel, Higgs, Stephen, Barrett, Alan D. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942996/
https://www.ncbi.nlm.nih.gov/pubmed/35322047
http://dx.doi.org/10.1038/s41541-022-00460-6

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