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LCZ696 ameliorates doxorubicin-induced cardiomyocyte toxicity in rats

Doxorubicin (DOX)-based chemotherapy induces cardiotoxicity, which is considered the main bottleneck for its clinical application. In this study, we investigated the potential benefit of LCZ696, an angiotensin receptor–neprilysin inhibitor against DOX-induced cardiotoxicity in rats and H9c2 cells an...

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Detalles Bibliográficos
Autores principales:	Miyoshi, Toru, Nakamura, Kazufumi, Amioka, Naofumi, Hatipoglu, Omer F., Yonezawa, Tomoko, Saito, Yukihiro, Yoshida, Masashi, Akagi, Satoshi, Ito, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943022/ https://www.ncbi.nlm.nih.gov/pubmed/35322164 http://dx.doi.org/10.1038/s41598-022-09094-z

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