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OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gα(z)

Heterotrimeric G proteins are the main signalling effectors for G protein-coupled receptors. Understanding the distinct functions of different G proteins is key to understanding how their signalling modulates physiological responses. Pertussis toxin, a bacterial AB(5) toxin, inhibits Gα(i/o) G prote...

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Detalles Bibliográficos
Autores principales: Keen, Alastair C., Pedersen, Maria Hauge, Lemel, Laura, Scott, Daniel J., Canals, Meritxell, Littler, Dene R., Beddoe, Travis, Ono, Yuki, Shi, Lei, Inoue, Asuka, Javitch, Jonathan A., Lane, J. Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943041/
https://www.ncbi.nlm.nih.gov/pubmed/35322196
http://dx.doi.org/10.1038/s42003-022-03191-5