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Effect of hydrophobic moment on membrane interaction and cell penetration of apolipoprotein E-derived arginine-rich amphipathic α-helical peptides

We previously developed an amphipathic arginine-rich peptide, A2-17, which has high ability to directly penetrate across cell membranes. To understand the mechanism of the efficient cell-penetrating ability of the A2-17 peptide, we designed three structural isomers of A2-17 having different values o...

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Detalles Bibliográficos
Autores principales:	Takechi-Haraya, Yuki, Ohgita, Takashi, Kotani, Mana, Kono, Hiroki, Saito, Chihiro, Tamagaki-Asahina, Hiroko, Nishitsuji, Kazuchika, Uchimura, Kenji, Sato, Takeshi, Kawano, Ryuji, Sakai-Kato, Kumiko, Izutsu, Ken-ichi, Saito, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943082/ https://www.ncbi.nlm.nih.gov/pubmed/35322082 http://dx.doi.org/10.1038/s41598-022-08876-9

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