Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice

The lymphatic vasculature is critical for lung function, but defects in lymphatic function in the pathogenesis of lung disease is understudied. In mice, lymphatic dysfunction alone is sufficient to cause lung injury that resembles human emphysema. Whether lymphatic function is disrupted in cigarette...

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Detalles Bibliográficos
Autores principales: Summers, Barbara D., Kim, Kihwan, Clement, Cristina C., Khan, Zohaib, Thangaswamy, Sangeetha, McCright, Jacob, Maisel, Katharina, Zamora, Sofia, Quintero, Stephanie, Racanelli, Alexandra C., Redmond, David, D’Armiento, Jeanine, Yang, Jisheng, Kuang, Amy, Monticelli, Laurel, Kahn, Mark L., Choi, Augustine M. K., Santambrogio, Laura, Reed, Hasina Outtz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943143/
https://www.ncbi.nlm.nih.gov/pubmed/35322079
http://dx.doi.org/10.1038/s41598-022-08617-y

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