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eIF6 rebinding dynamically couples ribosome maturation and translation

Protein synthesis is a cyclical process consisting of translation initiation, elongation, termination and ribosome recycling. The release factors SBDS and EFL1—both mutated in the leukemia predisposition disorder Shwachman-Diamond syndrome — license entry of nascent 60S ribosomal subunits into activ...

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Detalles Bibliográficos
Autores principales:	Jaako, Pekka, Faille, Alexandre, Tan, Shengjiang, Wong, Chi C., Escudero-Urquijo, Norberto, Castro-Hartmann, Pablo, Wright, Penny, Hilcenko, Christine, Adams, David J., Warren, Alan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943182/ https://www.ncbi.nlm.nih.gov/pubmed/35322020 http://dx.doi.org/10.1038/s41467-022-29214-7

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