Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection

Senecavirus A (SVA) is a cause of vesicular disease in pigs, and infection rates are rising within the swine industry. Recently, anthrax toxin receptor 1 (ANTXR1) was revealed as the receptor for SVA in human cells. Herein, the role of ANTXR1 as a receptor for SVA in pigs was investigated by CRISPR/...

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Detalles Bibliográficos
Autores principales: Chen, Paula R., Rowland, Raymond R. R., Stoian, Ana M., Petrovan, Vlad, Sheahan, Maureen, Ganta, Charan, Cino-Ozuna, Giselle, Kim, Dae Young, Dunleavey, James M., Whitworth, Kristin M., Samuel, Melissa S., Spate, Lee D., Cecil, Raissa F., Benne, Joshua A., Yan, Xingyu, Fang, Ying, Croix, Brad St., Lechtenberg, Kelly, Wells, Kevin D., Prather, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943192/
https://www.ncbi.nlm.nih.gov/pubmed/35322150
http://dx.doi.org/10.1038/s41598-022-09123-x

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